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LUS in Acute Heart Failure Therapeutic Adaptation

Interest of Lung Ultrasound (LUS) in Therapeutic Adaptation of Patients Hospitalized in Medical Department for Acute Heart Failure (AHF).

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04633629
Acronym
EPPICA
Enrollment
94
Registered
2020-11-18
Start date
2020-12-31
Completion date
2021-10-31
Last updated
2020-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Heart Failure, Pulmonary Congestion

Keywords

Lung Ultrasound, Diuretics, Medical department

Brief summary

Evaluate lung ultrasound aspect according to diuretics dosage evolution in patients hospitalized for acute heart failure.

Detailed description

EPPICA is an observational and prospective cohort study. The study goal is to evaluate LUS aspect evolution according to diuretics dosage in patients hospitalized for acute heart failure.

Interventions

OTHERLung ultrasound

We will perform daily a lung ultrasound to evaluate pulmonary congestion by counting B-lines.

Sponsors

University Hospital, Grenoble
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Acute heart failure diagnosed by a senior physician in the medical department, with a confirmation of a second senior physician. * Hospitalised in the medical department. * No objection from the patient of his trusted person.

Exclusion criteria

* Administrative supervision or deprived of their liberty * Pulmonary conditions distracting lung ultrasound (pneumonectomy, pulmonary fibrosis) * Chronically dialysed

Design outcomes

Primary

MeasureTime frameDescription
Lung ultrasound aspect according to diuretics dosage evolution.LUS will be performed daily during the whole hospitalisation length (on average 7 days).B-lines number on LUS

Secondary

MeasureTime frameDescription
Lung ultrasound aspect according to clinical signs of acute heart failure (crackling auscultation or lower limbs edema)LUS and clinical examination will be performed daily during the whole hospitalisation length (on average 7 days).B-lines number on LUS
Lung ultrasound aspect according to acute kidney injury (based on plasmatic creatinine levels).LUS will be performed daily during the whole hospitalisation length (on average 7 days). Plasmatic creatinine measure will be performed at least weekly.B-lines number on LUS
Lung ultrasound aspect according to early prognosis (re-hospitalisation or mortality within 30 days after discharge)LUS will be performed daily during the whole hospitalisation length (on average 7 days). Patient will be called 30 days after discharge.B-lines number on LUS
Feasibility of daily LUS in medical department.LUS will be performed daily during the whole hospitalisation length (on average 7 days).Number of LUS performed compared to number of hospitalisation days.
Interest of LUS compared to clinical examination at discharge.LUS and clinical examination will be performed daily during the whole hospitalisation length (on average 7 days).B-lines at discharge compared to clinical signs of acute heart failure.

Contacts

Primary ContactPerrine Dumanoir, Doctor
pdumanoir@chu-grenoble.fr+33476767098
Backup ContactMélanie Arnaud
marnaud3@chu-grenoble.fr+3376767098

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026