Biliary Stricture, Cholangiocarcinoma, Cholangitis; Choledocholithiasis
Conditions
Keywords
Fast track, Enhanced recovery after surgery, biliary surgery
Brief summary
The aim of the study is to improve the immediate results after reconstructive and restorative operations on the biliary tract by substantiating the management of the perioperative period on the principles of enhanced recovery after surgery.
Detailed description
A prospective randomized study on the effect of fast-track surgery on the immediate postoperative results after various reconstructive and restorative operations on the bile ducts. In the Department of Surgical Hepatology and Transplantation, a prospective randomized study will include patients (about 50) with planned reconstructive and restorative operations on the bile ducts for malignant and benign diseases of the bile ducts.
Interventions
COMBINATION_PRODUCTEnhanced recovery after biliary tract surgery
Patients with malignant and benign diseases of the bile ducts, who have formed various types of anastomosis in two options for managing the postoperative period: traditional and based on the principles of enhanced recovery after surgery
Sponsors
Vitebsk State Medical University
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
1. Patients with malignant diseases of the biliary tract (cholangiocarcinoma): 1.1. tumor resectability 1.2. absence: * distant metastases * carcinomatosis * perforation of the tumor and peritonitis * sprouting into adjacent organs and tissues (locally advanced cancer) * total adhesion process in the abdominal cavity (after previous operations). 1.3. Planned reconstructive surgery on the biliary tract. 2. Patients with benign biliary tract pathology. 2.1. Planned reconstructive or restorative surgery on the biliary tract for the following diseases: * choledocholithiasis * Mirizzi syndrome * cysts of the common bile duct * strictures of the common bile duct * injuries to the bile ducts * adenoma and stricture of the OBD
Exclusion criteria
1. Scale ASA\> III (severe concomitant cardiovascular pathology). 2. Palliative reconstructive surgery. 3. Previously performed operations on the bile ducts (up to 1 month). 4. Cachexia.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Reduction of bed-days | 1 week | Improvement of basic health indicators, absence of complications, reduction of bed days |
Contacts
Primary ContactYury N Arlouski, MD
Outcome results
None listed