Surgery
Conditions
Brief summary
The anastomotic leak (AL) is a very serious complication in colorectal surgery not only because of its severity but its frequency. Other facet for study, besides the risk factor and prevention, is the AL early diagnostic, due to minimize the clinical consequences and severity; and avoid the failure-to-recue. Several studies analyze the Creactive protein (CRP) and Procalcitonine (PCT) usefulness in AL predictor before the clinical signs appear. At a prospective observational study carry on our center, it concluded that CRP at 3rd day after surgery over 15mg/dl was a very important AL predictor, even before the clinical changes appear. The aim of this study is minimize the severity complications and the mortality due to AL appears. The aim of this study is minimize the severity complications and the mortality due to AL by means of introduces an upgrade program in which a CT scan will be conduct in all the patients with high CRP levels at 3rd, 4th or 5th postoperative day, with the goal to know the AL early and make all the therapeutic step to minimize the consequences.
Interventions
OTHEREarly diagnosis
Early diagnosis. Upgrade program implementation.
Sponsors
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients over 18 years of age. * Patients undergoing elective colorectal surgery due to neoplastic or non-neoplastic etiology. * Patients with an anastomosis performed in the surgical act. * Signed informed consent.
Exclusion criteria
* Patients who require transfer to another center. * Patients with fatal evolution: those who require urgent reoperation for an inarverted perforation, early leakage of anastomosis or death before the third postoperative day.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Severity of morbidity | 1 year | Number of reoperations, readmissions for infections associated or other medical complications, terminal stomata |
| Severity of mortality | 1 year | Number of related exits |
Secondary
| Measure | Time frame |
|---|---|
| - Compare hospital stay and ICU stay of patients undergoing elective colorectal surgery before and after the improvement program. | 1 year |
| - Evaluate the difference in the incidence of anastomosis leak after the implementation of the improvement program | 1 year |
Countries
Spain
Contacts
Primary ContactGraciela Valero-Navarro, MD
Outcome results
None listed