Brain Activity
Conditions
Keywords
attention deficit hyperactivity disorder, networks, magnetoencephalography, developmental delay, children
Brief summary
Investigate the differences in activation of brain networks during performing functional tasks for children with attention deficit hyperactivity disorder with developmental delays and typical development
Detailed description
A total of 12 children with attention deficit hyperactivity disorder with developmental delays and12 children with typical development will be enrolled. The following evaluations will be evaluated by the investigator who is blinded to the group's classification. Working task-related functions, such as Beery-Buktenica Visual-Motor Integration, Sensory Profile, the Chinese version of Swanson, Nolan and Pelham version IV, and Chinese version of Wechsler Intelligence Scale for Children-IV) Non-working memory-related functions, such as Pediatric Outcome Data Collection Instrument (PODCI), Child Health Questionnaire- Parent Form (CHQ-PF 28), Pediatric Quality of Life Inventory (PedsQL), and physical function (10 meters normal and fast walking, stair ascent, stair descent, and 5 times chair rising and timed up and go test) All participants will be investigated by magnetoencephalography and eye-tracking system to identify the difference of brain network activation during resting and performing tasks and between-group differences. Brain magnetic resonance image study will be performed for matching of brain localization.
Interventions
OTHERBrain networks activity
The brain network activity under different conditions will be evaluated by magnetoencephalography, including resting, listen to different types of music, watch different types of videos, and interacting with cognitive stimulation conditions.
Sponsors
Taipei Medical University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
4 Years to 10 Years
Healthy volunteers
Yes
Inclusion criteria
* children with attention deficit hyperactivity disorder with development delays * intelligence quotient 70 or greater
Exclusion criteria
* age less than 4 or greater than 10 of children * intelligence quotient less than 70
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Brain network activity by magnetoencephalograph | measure simultaneous brain activity by different types of music through study completion, up to 6 minutes | magnetoencephalography by different types of music |
| Brain network activity by magnetoencephalography | measure simultaneous brain activity by different types of videos through study completion, up to 10.5 minutes | magnetoencephalography by different types of videos |
Other
| Measure | Time frame | Description |
|---|---|---|
| Swanson, Nolan and Pelham | before magnetoencephalography examination | assess the symptoms of attention deficit hyperactivity disorders, 0-78, higher scores mean a worse outcome |
| Wechsler Intelligence Scale for Children | before magnetoencephalography examination | assess the intelligence, 40-160, higher scores mean a better outcome |
| Pediatric Outcome Data Collection Instrument | before magnetoencephalography examination | assess the functional performance, 0-100, higher scores mean a better outcome |
| Child Health Questionnaire- Parent Form | before magnetoencephalography examination | assess the family impact, 0-100, higher scores mean a better outcome |
| Beery-Buktenica Visual-Motor Integration | before magnetoencephalography examination | assess visual motor function |
| 10 meters walking speed | before magnetoencephalography examination | assess normal and fastest walking speed |
| stairs climbing time | before magnetoencephalography examination | assess ascent and descent stairs time |
| chair-rising time | before magnetoencephalography examination | assess 5 times of chair-rising time |
| timed up and go | before magnetoencephalography examination | assess time for stand up from a chair, go around for 3 meters, and sit down to chair |
| Pediatric Quality of Life Inventory | before magnetoencephalography examination | assess the health-related quality of life, 0-100, higher scores mean a better outcome |
| Sensory Profile Questionnaire | before magnetoencephalography examination | assess sensory integration,15 to 85, higher scores mean a better outcome |
Countries
Taiwan
Contacts
Primary ContactRu-Lan Hsieh, MD
Backup ContactRu-Lan Hsieh, MD
Outcome results
None listed