EFFECT OF PRE EXTUBATION MANUAL HYPERINFLATION TECHNIQUE VS REGULAR EXTUBATION AFTER STERNOTOMY

Effects of Pre-extubation Manual Hyper Inflation in Comparison to Regular Extubation Following Sternotomy.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04626180

Enrollment

Registered

2020-11-12

Start date

2017-09-01

Completion date

2018-06-01

Last updated

2020-11-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sternotomy

Keywords

Sternotomy, Extubation, Manual Hyperinflation

Brief summary

Post operative pulmonary complication (PPC) is one of the cause of mortality and morbidity after sternotomy. There is no accessible confirmation which shows the impact of Pre Extubation Manual Hyperinflation method with Regular Extubation procedure. After sternotomy manual hyperinflation technique is not taken during extubation. The objective of the study was to determine the effect of Pre Extubation Manual Hyperinflation technique VS regular Extubation technique on vitals and respiratory parameters in patients after Sternotomy.

Interventions

PROCEDUREExtubation

Extubation is the removal of an endotracheal tube (ETT), which is the last step in liberating a patient from the mechanical ventilator.

PROCEDUREManual Hyperinflation

Providing a larger tidal volume than baseline tidal volume to the patient and using a tidal volume which is 50% greater than that delivered by the ventilator

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

40 Years to 60 Years

Healthy volunteers

Inclusion criteria

1. Age 40 to 60 2. Patient undergone surgery (sternotomy) 3. Elective intubated (ETT orally) 4. Ventilated more than 3 hours -

Exclusion criteria

1. Patient with any neurological issue (mentally disturbed) who cannot understand the command 2. Complicated extubation 3. Pulmonary pathology where lung hyperinflation was contra-indicated (e.g. acute respiratory distress syndrome, undrained pneumothorax or exacerbation of chronic obstructive pulmonary disease and acute pulmonary edema. 4. Raised intracranial pressure 5. Redo or reopen. -

Design outcomes

Primary

Measure	Time frame
Peak expiratory flow rate	1 day
Blood pH	1 day
Blood pO2	1 day
Blood pCO2	1 day
Blood pHCO3	1 day
Pulse rate	1 day
Oxygen saturation	1 day
Forced expiratory volume	1 day
Forced vital capacity	1 day

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026