Non-contact DCS-Speckle Multi-parameter Imaging for Neurological Diseases

Clinical Applications for Non-contact DCS-Speckle Multi-parameter Imaging for Brain Injuries and Brain Edema

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04623307

Enrollment

Registered

2020-11-10

Start date

2020-11-01

Completion date

2021-12-31

Last updated

2020-11-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain Edema, Brain Injuries, Optical Imaging

Keywords

DCS-Speckle, Brain injuries, Brain edema

Brief summary

This study aims to evaluate brain injuries and brain edema with non-contact DCS-Speckle multi-parameter imager.

Detailed description

Brain injuries includes acute and chronic injuries located in cerebral hemispheres, cerebellum, and brain stem, while brain edema is increased intracellular or extracellular fluid in brain tissue. Early diagnosis is helpful to improve the cure rate and reduce sequelae. This study aims to evaluate brain injuries and brain edema with non-contact DCS-Speckle multi-parameter imager, so as to provide reference diagnostic criteria by image artificial intelligence analysis.

Interventions

DIAGNOSTIC_TESTNon-contact DCS-Speckle multi-parameter imaging

The protocol consists of 2-min resting, 6-min stationary state and 2-min resting, with monitoring data continuously by the DCS-Speckle.

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* Patients who have had brain damage. * Patients who have had brain edema. * Healthy people who are interested in non-contact DCS-Speckle multi-parameter imaging

Exclusion criteria

* Patients who are in pregnancy or have plan to conception. * Patients who have vertebra surgery or have plan to surgery. * Patients who are inappropriate to join this trial judged by the radiologists or specialists. * AIDS, Active Hepatitis, Tuberculosis, Syphilis * Patients who regularly take anticoagulants, antiplatelet drugs

Design outcomes

Primary

Measure	Time frame	Description
Imaging data	1 day during the whole experiment	Imaging data collected during the non-contact DCS-Speckle imaging instrument

Secondary

Measure	Time frame	Description
Diagnostic report fMRI data	1 day during the whole experiment	Patients' medical record and diagnostic report

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026