Verruca Vulgaris
Conditions
Brief summary
To assess the efficacy (clinically and dermoscopically) and safety of photodynamic therapy using intralesional injection of 4% methylene blue solution as a photosensitizer with IPL versus IPL only in treatment of warts.
Detailed description
This study will be conducted on: Eighty patients suffering of verruca (male and female) divided randomly into three groups: group A, B&C : Group A: 30 patients will undergo photodynamic therapy using intralesional 4%methylene blue solution and IPL. Group B: 30 patients will undergo IPL only. Group C (control group):20 patients will undergo intralesional saline.
Interventions
Sponsors
Alexandria University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. Age:Above 16 years old. 2. Sex:Both males and female patients. 3. Clinically and dermoscopically documented verruca. 4. No verruca treatment in the last 2 weeks.
Exclusion criteria
1. History of photosensitivity disorder. 2. Pregnant and lactating females. 3. Diseases with risk of koebnerization e.g. Psoriasis and Lichen planus. 4. Anogenital warts. 5. Warts on head and neck.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| disappearance of verruca | 10 weeks | clinical and dermoscopic cure |
Countries
Egypt
Outcome results
None listed