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Impact of Immune Checkpoint Inhibitor Therapy on Type 2 Inflammation

Impact of Immune Checkpoint Inhibitor Therapy on Type 2 Inflammation

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04609930
Acronym
ImmunEO
Enrollment
143
Registered
2020-10-30
Start date
2020-10-30
Completion date
2021-08-31
Last updated
2021-12-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients Recieving Anti-PD-1 or Anti-PD-L1 Immunotherapies

Brief summary

The primary objective of this study is to determine the impact of anti-checkpoint immunotherapy on type 2 inflammation via a retrospective analysis of % eosinophilia.

Interventions

Immunotherapy treatment via anti programmed death 1 and/or anti-programmed death ligand 1.

Sponsors

University Hospital, Montpellier
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Electronic patient file DxCare at the University Hospitals of Montpellier * Patient has received anti-PD-1 immunotherapy --AND/OR -- anti-PD-L1 immunotherapy according to central pharmacy records

Exclusion criteria

* No mention of % eosinophilia in the patient file

Design outcomes

Primary

MeasureTime frame
Change in % eosinophilia after initiation of anti-PD-1 and/or anti-PD-L1Before treatment (before day 0) versus after (15 days)

Secondary

MeasureTime frameDescription
Indication leading to anti-PD-1 and/or anti-PD-L1 immunotherapiesDay 0Name of pathology
Age (years)Day 0
Sex (male/female)Day 0

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026