Cardiac Surgery Outcomes in Blood-transfusion Acceptors and no Acceptors

Cardiac Surgery Outcomes in Blood-transfusion Acceptors and no Acceptors: a Retrospective Cohort Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04609228

Enrollment

1911

Registered

2020-10-30

Start date

2020-10-30

Completion date

2022-10-01

Last updated

2022-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Transfusion; Hemoglobinemia, Cardiac Disease, Thoracic Surgery

Brief summary

The primary objective of this study is to analyze mortality after cardiac surgery in blood-transfusion non-acceptors (BTNA), and the secondary one to perform an adjusted comparison with a blood-transfusion acceptors (BTA) matched cohort.

Interventions

OTHERNon-acceptance of blood-transfusions

Patients who do not accept blood products transfusions

OTHERAcceptance of blood-transfusions

Patients who accept blood products transfusions

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 100 Years

Healthy volunteers

Inclusion criteria

* Patients undergoing heart surgery in our hospital from 2009 to June 2020

Exclusion criteria

* Preoperative hemoglobin lower than 120g/L * EuroSCORE-II higher than 20% * Heart transplant * Assist device implantation * Surgery of acute myocardial infarction-derived complications * Other emergent cardiac surgeries (acute aortic dissection, heart injuries).

Design outcomes

Primary

Measure	Time frame	Description
Change on Hemoglobin values from preoperative to end-of-surgery levels	End-of-surgery	Changes on Hemoglobin values in percentage from preoperative level to the end of the surgery level

Secondary

Measure	Time frame	Description
Rate of operative mortality	At discharge or within the first 30 postoperative days	Any death occurring i) within the first 30 postoperative days in or out of the hospital, and ii) after 30 days during the same hospitalization subsequent to the operation.
Intraoperative fluid balance	End of surgery	Resting the fluid outputs to inputs
Hemoglobin at discharge	At discharge, an average of 10 days	Hemoglobin level at discharge
Rate of postoperative morbidity	At discharge, an average of 10 days	Postoperative complications: hemodynamic, respiratory, renal, neurological, infective complications

Countries

Spain

Contacts

Primary ContactElena Roselló-Díez, MD, PhD

erosello@santpau.cat+34 935565957

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026