Nutritional Support, Catheterization, Post-pyloric Feeding Tube, Dysphagia
Conditions
Brief summary
To compare efficacy and safety of a new modified post-pyloric feeding tube bedside catheterization with Corpak 10-10-10 protocol and electromagnetic guided catheterization for treatment of patients with dysphagia and at high-risk of aspiration pneumonia. We conducted a single-center, single-blinded, and randomized controlled clinical trial. A total of 63 patients were treated with the non-gravity type CORFLO gastrointestinal feeding tube between 2017.1 and 2019.1 using different procedures: in the M group, patients underwent modified post-pyloric feeding tube bedside placement; in C group, patients underwent conventional Corpak protocol; in EM group, patients received standard electromagnetic guided tube placement.
Interventions
PROCEDUREA modified method for blind bedside placement of post-pyloric feeding tube.
Modified post-pyloric feeding tube bedside catheterization as an optimized bedside blind post-pyloric tube placement, significantly shortened the time for passing pylorus without causing any severe adverse reactions.
Sponsors
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Inclusion criteria
* All patients had dysphagia that could not be alleviated within 48 hours * High-risk status with aspiration pneumonia, including consciousness disorder caused by various diseases, severe dementia, bed rest, gastroesophageal reflux, hiccup, gastric retention, achalasia of pyloric. * Can't receive nasogastric tube feeding.
Exclusion criteria
* The previous history of upper abdominal surgery. * Gastroduodenal ulcer and esophagogastric varices; * Severe sinusitis and nasal bone fracture; * Patients with recent gastrointestinal bleeding, intestinal obstruction, ischemic bowel disease, and epistaxis; * Patients with electromagnetically-guided catheterization should additionally exclude implantable cardiac defibrillator, implantable cardiac pacemaker or diaphragm pacemaker.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The success rate of NIT placement | 2019.10 | The successful catheterization was defined when the catheter tip was placed behind the pylorus. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Operation time of tube insertion | 2019.10 | The time spent on the catheterization. |
Other
| Measure | Time frame | Description |
|---|---|---|
| The time for passing pylorus and the depth of insertion | 2019.10 | The time the catheterization passes through the pylorus. |
| Serious complications | 2019.10 | asphyxiation, hemoptysis, and exacerbation of aspiration pneumonia |
Outcome results
None listed