Bowel Preparation
Conditions
Keywords
bowel preparation; face-to-face instruction; personalized intervention
Brief summary
background:The use of enhanced instruction can improve the efficiency of education for bowel preparation regimens. Researchers hypothesized that face-to-face instruction and personalized intervention for inpatient could improve successful bowel preparation rate and patient's compliance with regimens. Methods:This was an endoscopist-blind,randomized controlled trial. 320inpatients were randomized 1:1 in one of the two study groups. The intervention group received face-to-face instruction and personalized intervention for bowel preparation protocol, while control group received the standard bowel preparation protocol. Patients'demographics, bowel preparation quality, colonoscopy completion and attendance were recorded. Logistic regression was performed to identify predictors of bowel preparation failure.
Interventions
DRUGPEG-FFI
Patients with risk factor : on the day before the colonoscopy at 20:00- 21:00 hours, 60gPEG-4000 was mixed with 1L water; 4-6 h before colonoscopy, 120gPEG-4000 was mixed with 2L water. Patient without risk factor: 4-6 hours before colonoscopy, 120gPEG-4000 was mixed with 3L water. Education completed by experienced researcher.
DRUGPEG-nonFFI
All patients on the day of the colonoscopy:4-6 hours before colonoscopy, 120gPEG-4000 was mixed with 3L water. Education completed by ward nurse.
Sponsors
Ningbo No. 1 Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Inpatients undergoing colonoscopy. * patients older than 18 years.
Exclusion criteria
* prior surgery of colorectal resection; * suspected colonic stricture or perforation; * incomplete or complete bowel obstruction; * use of prokinetic agents or purgatives within 7 days; * Patients with severe gastrointestinal diseases, such as intestinal obstruction or perforation, active ulcerative colitis, toxic colitis and toxic megacolon;; * pregnancy or lactation; * Inability to prepare bowel; * unable to give informed consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Quality of Bowel Preparation | 1 Day of colonoscopy | The BBPS is a validated scoring system with scores between 0 and 9, where 9 is the best score. The score comprises a sub score 0-3 for each colon segment: right, transverse and left colon. For all participants, BBPS score will be used when colonscopy is withdrawing. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| adverse events | The day of colonoscopy and the day before | Including nausea, vomiting, abdominal pain and bloating,etc. |
| cecal intubation rate | 1 Day of colonoscopy | The number of colonoscopy reaching the cecal area divided by the total number of colonoscopy |
| polyp detection rate | 1 Day of colonoscopy | PDR was defined as the number of patients with at least one polyp divided by the total number of colonoscopy patients |
| cecal intubation time | 1 Day of colonoscopy | Time to reach the cecal |
| withdrawal time | 1 Day of colonoscopy | Time from withdrawal from the cecum to the end of colonoscopy |
Countries
China
Outcome results
None listed