Cardiac Surgery, Cardiac Output
Conditions
Keywords
Hemodynamic Monitoring, Pulmonary artery catherization, LiDCO
Brief summary
1. To evaluate the consistency of cardiac output measured by pulmonary artery catheter and LiDCO in cardiac surgical patients 2. To evaluate whether different hemodynamic monitoring methods can accurately detect the trend of cardiac output changes
Detailed description
Close monitoring of cardiac output (CO), especially in patients before and after intervention(such as volume expansion, diuresis, vasoconstriction, vasodilation therapy), could help to adjust the treatment strategy in cardiac surgical patients. Pulmonary artery catherization (PAC) has been used for hemodynamic monitoring for more than four decades. In spite of its invasiveness, it remains the clinical reference method for the assessment of CO at the bedside. Nowadays, many less invasive alternatives, such as LiDCO Rapid Pulse Contour Analysis System (LiDCO Ltd., Cambridge, United Kingdom), are already available on market. However, consistency between different hemodynamic monitoring results still raise concern. And whether hemodynamic monitoring could accurately detect the changes of these parameters before and after intervention is an important issue in clinical practice. In this study, the investigators are going to collect CO and changes of CO from PAC and LiDCO before and after intervention (passive leg raising and dobutamine stress test) in cardiac surgical patients. Our resulst could provide important reference for cardiac surgical patients how to choose appropriate hemodynamic monitoring tools and how to interpret the results of hemodynamic monitoring.
Interventions
Passive leg raising is induced by rasing the legs of patients to 45° from horizontal position.
Dobutamine was infused intravenously at the initial dose of 2.5 ug/kg/min. hemodynamic data were recorded from PAC and LiDCO after 5-10 minutes of continuous infusion.
Sponsors
Study design
Eligibility
Inclusion criteria
1. cardiac surgery 2. hemodynamic monitoring (PAC, LiDCO) 3. mechanical ventilation
Exclusion criteria
1. cardiac arrhythmia 2. moderate to severe aortic, mitral and tricuspid regurgitation 3. IABP 4. ECMO
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Baseline Cardiac Output measurement | within1 minute at baseline position | Cardiac Output measured at baseline position (horizontal position) |
| Cardiac Output measurement after PLR | 1 minute after PLR | Cardiac Output measured after PLR |
| Cardiac Output measurement after Dobutamine stress test | 5 minutes after dobutamine stress test | Cardiac Output measured after dobutamine stress test |
Countries
China