Hypotension on Induction
Conditions
Brief summary
Children generally undergo induction of anesthesia by inhalation of sevoflurane. Children with Down Syndrome experience bradycardia with induction of anesthesia using sevoflurane. It is unknown if this bradycardia is isolate or results in hypotension, thus requiring treatment. Isolate bradycardia without hypotension does not require treatment and should be avoided as many of these patients have underlying cardiac anomalies.
Detailed description
Children generally undergo induction of anesthesia by inhalation of sevoflurane. This is particularly relevant for children with developmental delays as to avoid placement of an IV while awake. However, children with Down Syndrome experience bradycardia with induction of anesthesia using sevoflurane. It is unknown if this bradycardia is isolate or results in hypotension, thus requiring treatment. Isolate bradycardia without hypotension does not require treatment and should be avoided as many of these patients have underlying cardiac anomalies.
Interventions
measurement of blood pressure during induction of general anesthesia
Sponsors
Baylor College of Medicine
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Weeks to 18 Years
Healthy volunteers
No
Inclusion criteria
Children \<18 years old Requiring general anesthesia with inhalation induction Down syndrome ASA physical classification 1-3
Exclusion criteria
Patients \>18 years of age Patients without down syndrome Cyanotic congenital heart disease Use of antihypertensive medications Pulmonary hypertension patients undergoing intravenous induction of anesthesia ASA physical classification other than 1-3 emergency procedure
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Assessment of non-invasive blood pressure during induction | 5 minutes | non invasive blood pressure during induction (systolic, diastolic and Mean pressures) |
Countries
United States
Outcome results
None listed