Hirschsprung Disease, Infants, Nutrition Supporting, Prospective Study
Conditions
Brief summary
A multi-center, prospective,randomized, non-blind, controlled study was conducted to investigate the effects of different pre-operative nutritional support modes on perioperative nutritional status, surgical treatment success rate, and rehabilitation process in children with Hirschsprung disease.
Interventions
DIETARY_SUPPLEMENTsupplement nutritional supporting
Special medical formula for the purpose of formula food
Sponsors
Tongji Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
0 Years to 5 Years
Healthy volunteers
No
Inclusion criteria
1. Children aged 0-5 years. 2. Clinical diagnosis with Hirschsprung's disease who requires surgery;
Exclusion criteria
1. Complicated with severe complications such as enterocolitis associated with Hirschsprung disease; 2. History of diseases associated with various organ systems that may be life-threatening; 3. Other severe digestive tract malformations or other diseases that may interfere with the treatment or compliance of the child; 4. Patients who have participated in other clinical trials within the last 1 month; 5. Any other conditions in which the investigator considers it inappropriate to participate in the trial.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| rate of postoperative HAEC | 3 months | Incidence of postoperative HAEC |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Z score | 3 months | weight/age |
| LOS | 1 months | length of postoperative stay |
| reoperation | 3 months | rate of reoperation |
| readmission | 3 months | rate of readmission |
Countries
China
Outcome results
None listed