Chronic Pain, Complex Regional Pain Syndromes
Conditions
Brief summary
Complex regional pain syndrome, CRPS, is an uncommon but often very disabling chronic pain syndrome characterized by, beside pain: sensory disturbances, peripheral autonomic changes and inflammatory features. The diagnosis is subdivided in CRPS type 1 where no nerve injury has been identified, and CRPS type 2 when a major nerve injury has been verified. A combination of exposure in vivo, a form of behaviour therapy where the patient is gradually confronted with avoided movements and activities, and interventions directly targeting a hypothesized cortical reorganisation is an interesting novel approach for treating CRPS. The present study consists of (1) a qualitative interview study with 10-15 subjects that has received this form of treatment, in order to better understand their experience and effects of the treatment, and (2) a case series with long-term follow-up of 3-5 subjects that received the treatment för 5-8 years ago, in order to study the long term effects of the treatment.
Interventions
BEHAVIORALMultimodal rehabilitation
A combination of exposure in vivo and interventions directly targeting the cortical reorganization for treating CRPS.
Sponsors
Uppsala University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Inclusion criteria
* Has participated in multimodal treatment for CRPS at Uppsala University Hospital
Exclusion criteria
* Other serious physical or mental condition
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diagnosis | 1 day | Whether the subject still fulfill diagnostic criteria for CRPS |
| Subjective experience | 1 day | A qualitative interview targeting the subjects own experience of the treatment and its effect |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Global impression of change | 1 day | Global impression of change measured with a single question (0-6, higher scores mean a better outcome) |
| Acceptance of pain | 1 day (0-156, higher scores mean a better outcome) | Measured with the Chronic Pain Acceptance Questionnaire, CPAQ (0-156, higher scores mean a better outcome) |
| Fear of pain | 1 day (0-52, lower scores mean a better outcome) | Measured with the Tampa Scale of Kinesiophobia, TSK (0-52, lower scores mean a better outcome) |
| Pain catastrophizing | 1 day (0-52, lower scores mean a better outcome) | Measured with Pain Catastrophizing Scale, PCS (0-52, lower scores mean a better outcome) |
| Level of pain | 1 day | Subjective level of pain on a Likert-scale 0-10 (NRS) |
| Neglect of the affected limb | 1 day (0-36, lower scores mean a better outcome) | Measured with a five item questionnaire (0-36, lower scores mean a better outcome) |
| Subjective experience of quality of life 2 | 1 day | EuroQol 5D, EQ-5D (0-15, higher scores means a better outcome) |
| Subjective experience of quality of life 3 | 1 day | Life Satisfaction Questionnaire, LiSat 11 (11-66, higher scores means a better outcome) |
| Avoidance of activities | 1 day (0-100, lower scores mean a better outcome) | Measured with the Photograph Series of Daily Activities, PHODA (0-100, lower scores mean a better outcome) |
| Subjective experience of quality of life | 1 day | Quality of life, measured with the RAND-36 (0-100, higher scores mean a better outcome) |
Countries
Sweden
Outcome results
None listed