Alzheimer Disease, Healthy, Semantic Dementia
Conditions
Brief summary
This study aims at exploring patients' ability to monitor their own memory performance depending on their primary deficit and the type of memory involved in the criterion task. The goal is to evaluate if semantic dementia (SD) and Alzheimer's disease (AD) differently affect patients' awareness of their memory abilities.
Detailed description
Patients who will give their informed non-opposition will be included. Participants will undergo 6 metacognitive tasks in which they will be tested on newly learnt information (i.e., episodic memory) or prior knowledge (i.e., semantic memory) and asked to evaluate their performance either prior or after the test. Correlation between their evaluation and their actual performance will be measured. Performance and correlations will be compared across groups.
Interventions
OTHERMetacognition tests
Test on episodic or semantic memory
Sponsors
University Hospital, Grenoble
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* native French-speakers * normal or corrected-to-normal vision * for patients ONLY : doctor-approved diagnosis of semantic dementia or Alzheimer's disease * for healthy participants ONLY: score above 27 on the MMSE * non-opposition in participation
Exclusion criteria
* other neurological/ psychiatric disorder, or cognitive disorder that might affect general cognition * drug or alcohol abuse
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Metacognitive bias on the episodic predictive judgment task | End of study : around May 2022 | Metacognitive bias will be assessed by subtracting the mean proportion of the metacognitive judgments to the actual memory performance. Bias will range from -1 (underestimation) to 1 (overestimation). |
| Metacognitive accuracy on the episodic predictive judgment task | End of study : around May 2022 | Metacognitive accuracy will be assessed by calculating a gamma correlation for each participant. Metacognition accuracy allows to evaluate people's ability to discriminate correct responses from incorrect responses. Gamma correlation range from -1 to 1. |
| Metacognitive bias on the semantic predictive judgment task | End of study : around May 2022 | Metacognitive bias will be assessed by subtracting the mean proportion of the metacognitive judgments to the actual memory performance. Bias will range from -1 (underestimation) to 1 (overestimation). |
| Metacognitive accuracy on the semantic predictive judgment task | End of study : around May 2022 | Metacognitive accuracy will be assessed by calculating a gamma correlation for each participant. Metacognition accuracy allows to evaluate people's ability to discriminate correct responses from incorrect responses. Gamma correlation range from -1 to 1. |
| Metacognitive bias on episodic global judgment task | End of study : around May 2022 | Metacognitive bias will be assessed by subtracting the mean proportion of the metacognitive judgments to the actual memory performance. Bias will range from -1 (underestimation) to 1 (overestimation). |
| Metacognitive bias on semantic global judgment task | End of study : around May 2022 | Metacognitive bias will be assessed by subtracting the mean proportion of the metacognitive judgments to the actual memory performance. Bias will range from -1 (underestimation) to 1 (overestimation). |
| Metacognitive bias on the episodic retrospective judgment task | End of study : around May 2022 | Metacognitive bias will be assessed by subtracting the mean proportion of the metacognitive judgments to the actual memory performance. Bias will range from -1 (underestimation) to 1 (overestimation). |
| Metacognitive accuracy on the episodic retrospective judgment task | End of study : around May 2022 | Metacognitive accuracy will be assessed by calculating a gamma correlation for each participant. Metacognition accuracy allows to evaluate people's ability to discriminate correct responses from incorrect responses. Gamma correlation range from -1 to 1. |
| Metacognitive bias on the semantic retrospective judgment task | End of study : around May 2022 | Metacognitive bias will be assessed by subtracting the mean proportion of the metacognitive judgments to the actual memory performance. Bias will range from -1 (underestimation) to 1 (overestimation). |
| Metacognitive accuracy on the semantic retrospective judgment task | End of study : around May 2022 | Metacognitive accuracy will be assessed by calculating a gamma correlation for each participant. Metacognition accuracy allows to evaluate people's ability to discriminate correct responses from incorrect responses. Gamma correlation range from -1 to 1. |
Countries
France, Switzerland
Outcome results
None listed