The Relationship Between the Tumor Markers and Interstitial Lung Disease

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04597814

Enrollment

Registered

2020-10-22

Start date

2019-01-01

Completion date

2020-10-15

Last updated

2020-10-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

the Relationship Between the Tumor Markers and Interstitial Lung Disease Patients

Keywords

carcinoembryonic antigen, carbohydrate antigen 19-9, carbohydrate antigen 125

Brief summary

Detailed description

The serum levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), CA125 are often increased in interstitial lung disease patients. This study was undertaken to investigate the source of these serum tumor markers.We hypothesis that these tumor markers are released from the lung. The broncholveolr lvge fluid levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), CA125 were measured in the interstitial lung disease patients before lung transplantation. The immunohistochemical test was performed in the specimen lung after lung transplantation.

Interventions

OTHERNo Intervention

No Intervention

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 80 Years

Healthy volunteers

Inclusion criteria

1.Interstitial lung disease patients for lung transplantation \-

Exclusion criteria

1. tumor 2. Interstitial lung disease patients could not be performed by lung transplantation

Design outcomes

Primary

Measure	Time frame	Description
serum levels of carcinoembryonic antigen (CEA)	6months	serum levels of carcinoembryonic antigen (CEA)
serum levels of carbohydrate antigen 19-9 (CA19-9)	6months	serum levels of carbohydrate antigen 19-9 (CA19-9)
serum levels of carbohydrate antigen 125(CA125)	6months	serum levels of carbohydrate antigen 125(CA125)
The alveolar lavage fluid levels of carcinoembryonic antigen (CEA)	1 week	The alveolar lavage fluid levels of carcinoembryonic antigen (CEA)
The alveolar lavage fluid levels of carbohydrate antigen 19-9 (CA19-9)	1 week	The alveolar lavage fluid levels of carbohydrate antigen 19-9 (CA19-9)
The alveolar lavage fluid levels of carbohydrate antigen 125	1 week	The alveolar lavage fluid levels of carbohydrate antigen 125
The lung tissue levels of carcinoembryonic antigen (CEA)	1 week	The lung tissue levels of carcinoembryonic antigen (CEA)
The lung tissue levels of carbohydrate antigen 19-9 (CA19-9)	1 week	The lung tissue levels of carbohydrate antigen 19-9 (CA19-9)
The lung tissue levels of carbohydrate antigen 125	1 week	The lung tissue levels of carbohydrate antigen 125

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026