Neonatal Adaptation
Conditions
Keywords
percentile, cerebral oxygenation, neonate, immediate after birth
Brief summary
Especially in neonates non-invasive methods are required for monitoring the complex changes during immediate transition after birth to improve assessment of neonate and eventually resuscitation. During this period especially, the brain is vulnerable and monitoring the brain and possible influencing factors of cerebral oxygenation and perfusion are of great interest. To initiate and guide therapies based on cerebral oxygenation, it is important to define reference ranges.
Interventions
OTHERNo Intervention
no intervention
Sponsors
Medical University of Graz
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
0 Minutes to 15 Minutes
Healthy volunteers
Yes
Inclusion criteria
* Term and preterm neonates observed routinely at the resuscitation desk * Decision to conduct full life support * Written informed consent * Neonates who require no respiratory or medical support
Exclusion criteria
* No decision to conduct full life Support * No written informed consent * Congenital malformation * Neonates who require respiratory and/ or medical support
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of cerebral tissue oxygen saturation (crSO2) level | At each minute from minute 1 to minute 15 after birth | To measure cerebral oxygenation with Root (O3 regional oxymetry, Masimo, USA) non-invasively and continuously during the first 15 minutes after birth and establish the reference ranges in term and preterm neonates. |
Countries
Austria
Outcome results
None listed