Sternal Wound Infection, Surgical Site Infection
Conditions
Brief summary
The aim of this study is to systematically explore the perioperative presence of P acnes in all layers of sternal wound incision as well as contamination of graft material and prosthetic valves during primary operation. Secondly, to compare if different regimes of antibiotics affects the bacterial growth. Cultures will be taken from the skin, subcutaneous, and from the implanted valve prostheses with a rayon swab.Graft and Felt material will, after being pressed subcutaneous for 15 sec, placed into prepared sterile bottles containing broth for aerobe and anaerobe cultures. Surgical gloves will be cultured.
Interventions
OTHERBacterial cultures taken during surgery.
Cultures taken from skin, subcutaneous tissue, surigal materials and surgical gloves at incision and after two hours.
Sponsors
Region Örebro County
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Open cardiac surgery; coronary artery bypass grafting, valve replacement/repair or a combination of these.
Exclusion criteria
* Skin conditions such as eczema, psoriasis. * Revision surgery * Aortic surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Bacterial growth, C acnes | Five months | Growth of C acnes in cultures taken both from patients and surgical materials used in the primary operation. |
| Bacterial growth, other | Five months | Growth of bacteria in cultures taken both from patients and surgical materials |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Difference between subgroups | Five months | Difference in bacterial growth between subgroups. |
Countries
Sweden
Outcome results
None listed