Bad Breath
Conditions
Keywords
halitosis, volatile sulphur compounds
Brief summary
This study is to analyze whether the candies can relieve or eliminate bad breath, both subjectively and objectively.
Detailed description
This study is to systematically examine an existing candy, which is easily available and is intended to relieve or eliminate bad breath. The main aim of the study is to determine the effectiveness of the candies on the subjective perception of bad breath. The secondary outcome of the study is to investigate whether there is actually a decrease in volatile sulphur compounds (VSC) in the exhaled air and also a decrease in bad breath during organoleptic measurement. The purpose of the study is to investigate whether the different candies can relieve or eliminate bad breath, both subjectively and objectively.
Interventions
OTHERIntake of 3 different candies against bad breath
Intake of 3 different candies against bad breath on three different days (2-days interval each) after artificially creating a temporary bad breath (by eating of chips and cheese); analysis of breathing during intake of candy both subjectively and objectively
Sponsors
Ricola Group AG Schweiz
University Hospital, Basel, Switzerland
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Intervention model description
Three different variants of a candy are being tested by each participant. The candies are randomly assigned to the subjects, so that each subject has tested each of the three candies once. Randomization creates a different order for each participant. The study will be carried out on three different days.
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Non- smoker * No general medical illness or medication
Exclusion criteria
* Allergies/intolerances to ingredients of the products used * Chronic diseases * Smoker * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Organoleptic analysis of breathing air sample | max 60 minutes at 3 different days | Assessment of the patient's bad breath on the basis of the subjective assessment of an investigator (scale of 0 to 5 (0, no odor; 1, questionable odor; 2, slight malodor; 3, moderate malodor; 4, strong malodor; 5, severe malodor)) |
| Measurement of volatile sulphur compounds (VSC) in ppb (parts per billion). | max 60 minutes at 3 different days | Assessment of the patient's bad breath on the basis of the objective assessment by a sulfide monitor (HaliSens® AI Analytical Innovations GmbH, Moosbach, Germany) |
Countries
Switzerland
Outcome results
None listed