Exercise Therapy, Inflammatory Bowel Diseases
Conditions
Brief summary
This is a prospective interventional study. The investigators will include patients in clinical remission who are on stable treatment. These IBD patients will be followed to analyze the effects of physical activity on their inflammatory disease. Different exercises will be offered to two separate groups of randomly distributed patients: the first group will perform muscle building exercises while the other group will be offered aerobic exercises.There will also be a control group that does not initially benefit from a specific physical activity program. However, this group will be integrated into one of the other two groups after the 10-week follow-up. All three groups will perform the same baseline tests. These will be of different types: physical tests, biological tests and quality of life questionnaires.
Interventions
OTHEREndurance training
This group will perform aerobic type exercises. Initially, patients will perform continuous exercises of progressive intensity in order to adapt to this kind of effort. Next, we will introduce interval exercises.
OTHERResistance training
Patients in this group will perform lower limb strengthening exercises to improve the maximum strength of different muscle groups.
Sponsors
University of Liege
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Patients in remission defined by a Harvey Bradshaw Index 5 in Crohn's disease (CD) and a clinical Mayo 3 with no sub-score \>1 in ulcerative colitis (RCUH) with stable treatment, without corticosteroid for 4 months. * Patients accepting the study protocol
Exclusion criteria
* Patients suffering from other pathologies (at the level of the digestive system, the cardiovascular system, as well as the musculoskeletal system: recent knee plasty, recent knee fractures, etc.), which can interfere with planned tests and activity programs. * Patients with more than 3 hours of sports activity per week * Pregnant, pregnant or nursing patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Progressive effort test on bicycle ergometer (VO2 max) | day 1 | This test allows to measure VO2 in ml/min/kg (thanks to respiratory gases) |
| Progressive effort test on bicycle ergometer (Heart rate) | day 1 | This test allows to measure resting and maximum heart rate (thanks to an ECG) and maximum aerobic power in Watt. |
| Progressive effort test on bicycle ergometer (Power) | day 1 | This test allows to measure maximum aerobic power in Watt. |
| Maximum force test (N/m) | Day 1 | This test will be performed using an isokinetic dynamometer. This evaluation will allow us to determine the maximum force of the quadriceps and hamstrings of each participant in N/m. |
| Blood sample | Day 1 | This type of tests includes biological monitoring to obtain information on biological parameters. |
| Saddle analysis | Day 1 | This type of tests includes biological monitoring to obtain information on biological parameters. |
| IBD-F | Week 1 | Participants will complete a questionnaire on fatigue perceived. |
| Godin Leisure Time exercise questionnaire | Week 1 | Participants will complete a questionnaire on the level of physical activity |
| Metabolic Equivalent Task questionnaire | Week 1 | Participants will complete a questionnaire on the level of inactivity |
| Short Food Frequency Questionnaire | Week 1 | Participants will complete a questionnaire on their dietary habits |
| EQ5D questionnaire | Week 1 | Participants will complete a questionnaire on their level of health |
| Short health scale questionnaire | Week 1 | Participants will complete a questionnaire to evaluate the level of the inflammatory bowel disease |
Countries
Belgium
Outcome results
None listed