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Prevention of Cardiovascular Diseases Caused by Complex Treatment of Patients With Primary Operated Breast Cancer

To Develop and Implement a Method for Medical Prevention of Cardiovascular Diseases Caused by Complex Treatment of Patients With Primary Operated Breast Cancer

Status
Completed
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04588935
Enrollment
100
Registered
2020-10-19
Start date
2019-07-01
Completion date
2023-02-07
Last updated
2023-02-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Women With Breast Cancer

Brief summary

To develop a method of medical prevention of cardiovascular diseases caused by cardiotoxicity against the background of complex treatment of patients with primary resectable breast cancer to reduce the risk of cardiovascular complications

Detailed description

Purpose of the study: to develop a method of medical prevention of cardiovascular diseases caused by cardiotoxicity against the background of complex treatment of patients with primary resectable breast cancer to reduce the risk of cardiovascular complications

Interventions

DRUGBisoprolol; Perindopril;

based on the results of the patient study, different drug therapy regimens for cardiovascular complications during chemotherapy will be proposed

Sponsors

State Institution Republican Scientific and Practical Center Cardiology, Belarus
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Healthy volunteers
No

Inclusion criteria

* women with breast cancer, with a morphologically confirmed diagnosis before the appointment of anticancer therapy.

Exclusion criteria

* presence of other oncological diseases

Design outcomes

Primary

MeasureTime frameDescription
development of cardiovascular diseases and complications4 yearshypertension, cardiomyopathy, arrhythmia's, myocardial infarction, heart failure

Countries

Belarus

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026