Anxiety Disorders
Conditions
Brief summary
This randomised controlled trial will evaluate the effect of a ketogenic diet vs a conventional diet on the symptoms of patients living with anxiety disorders using a validate self-reported inventory.
Detailed description
It has been theorized that ketogenic diet could improve symptom control in patients living with anxiety disorders. Animal models support this hypothesis but to this date, studies in humans are lacking. The investigators will randomise patients with a confirmed diagnosis of anxiety disorders to follow a ketogenic diet (\<50 grs of carbohydrate per day) or a conventional diet (50% carbohydrate, 30% lipids, 20% protein) for one month. Symptom control will be assessed weekly using Beck's inventory for Anxiety. Diet adherence will be measured using standardised food frequency logs and acetoacetate urine strips.
Interventions
OTHERDiet
\<50 grams of total carbohydrates per day. Monosaturated fats consumption will be encouraged over saturated fats.
Sponsors
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Randomised controlled trial
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with a confirmed diagnosis of Anxiety Disorder by Psychiatrist.
Exclusion criteria
* Patients with the diagnosis of drug abuse, cognitive impairment or dementia, porphyria, carnitine translocase deficiency and carnitine palmitoyl transferase deficiency.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Symptom control | One month | Total points in Beck's Inventory for Anxiety. Scores range between 0 to 63 and higher numbers mean a worse outcome. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Subjective self perceived control | One month | Self-assessed and reported symptom ranging between 0 - 100. Higher numbers mean a better outcome. |
Countries
Mexico
Outcome results
None listed