Hepatitis B, Chronic, Hepatitis C, HIV Infections, Sexually Transmitted Infection
Conditions
Keywords
HIV, Testing, Self-testing, Retesting, Early diagnosis, Counseling, Computer, Reminder, Short message service, Pre-exposure prophylaxis
Brief summary
Multicenter cohort study of individuals reporting behavioral risks of HIV acquisition, recruited among those presenting for testing for HIV and other sexually transmitted infections. Overarching goal: to study factors associated with uptake of HIV prevention and (re)testing services in medium-sized cities in Thailand. Primary objective: To estimate the incidence of HIV and other sexually transmitted infections (syphilis, chronic hepatitis B and C) among individuals presenting for retesting. Secondary objectives: * To evaluate the uptake of pre-exposure prophylaxis * To assess retention in the study * To evaluate client HIV knowledge * To describe HIV prevalence and characteristics of individuals newly diagnosed with HIV * To describe characteristics of individuals at risk of HIV infection * To assess the quality of the testing and referral services.
Detailed description
Testing and counseling for HIV, syphilis and other sexually transmitted infections is provided to consenting individuals. Components: interactive counseling program, self sampling (finger prick) under supervision, questionnaire (on a tablet computer) to assess risks of HIV acquisition, understanding of HIV transmission routes and pre-exposure prophylaxis, willingness to take pre-exposure prophylaxis if at risk of HIV, and satisfaction with regard to services provided. Referral to appropriate care facility of participants diagnosed with infection. HIV negative participants with significant risk of HIV are advised to come back for HIV retesting within 3 to 6 months and informed about pre-exposure prophylaxis.
Interventions
None listed
Sponsors
Expertise France-L'Initiative
French National Research Institute for Sustainable Development (IRD)
Institut de Recherche pour le Developpement
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
15 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Aged 15 years or more * Willing to be tested for HIV and other sexually transmitted infections * Able to understand the study and its procedures
Exclusion criteria
None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| HIV incidence | Through study completion, an average of 3 years | HIV incidence |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Participants initiating pre-exposure prophylaxis | Through study completion, an average of 3 years | Proportion of participants initiating pre-exposure prophylaxis among those at significant risk of HIV |
| Retention | Through study completion, an average of 3 years | Cumulative probability of retest |
| HIV knowledge | Through study completion, an average of 3 years | Answers to a self-constructed questionnaire assessing participants' knowledge of HIV transmission routes and pre-exposure prophylaxis, following counseling. The questionnaire is composed of one multiple-choice question on HIV transmission routes and three True/False questions on pre-exposure prophylaxis. The results will be reported item by item. Exploratory data analyses may be conducted using, for example, principal component analysis. |
Countries
Thailand
Contacts
Primary ContactGonzague Jourdain, MD, PhD
Backup ContactNicolas Salvadori, PhD
Outcome results
None listed