Factors Associated With CPC 1-2 in 110 Patients Admitted in French ICU for a Myocardial Infarction Complicated by an OHCA.

Factors Associated With Neurological Prognosis 30 Days After an ICU Admission for a Myocardial Infarction Complicated by an Out-of-Hospital Cardiac Arrest : an Observationnal Multicentric Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04584463

Acronym

ACR-MI

Enrollment

110

Registered

2020-10-14

Start date

2020-10-30

Completion date

2021-11-30

Last updated

2020-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coma, Myocardial Infarction, Neurologic Dysfunction, Outcome, Fatal, Out-Of-Hospital Cardiac Arrest

Brief summary

This study evaluate the association of some in-ICU factors with the neurological prognosis of patients admitted for an out-of-hospital cardiac arrest due to a myocardial infarction.

Detailed description

Pre-hospital factors associated with poor neurologic outcome are well known. Meanwhile, in-ICU factors for the first 24 hours may impact neurologic outcome. This observational study aim to study the factors such as ECLS, NSE dosage, therapeutic hypotermia... and their association with neurologic outcome in patient with myocardial infarction due to instable coronaropathy complicated by an out-of-+hospital cardiac arrest. This is designed to be a observationnal, prospective, multicentric national french study

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* aged of 18 years old or more * non opposition of the patient, or his family if he is unable to consent, after loyal and comprehensive explanation * patient admitted in ICU * the reason for admission is a resurected out-of-hospital cardiac arrest * the cause of the cardiac arrest is a type 1 myocardial infarction

Exclusion criteria

* refractory cardiac arrest (no flow \> 30 minutes in normothermia) * in-hospital cardiac arrest * pregnancy * patient under juridic protection * opposition of the patient, or of his family is he is unable to consent.

Design outcomes

Primary

Measure	Time frame	Description
Neurologic outcome (CPC)	30 day from in-ICU admission	Cerebral Performance Category Scale to assess neurologic outcome 1-2 : good outcome 3-4-5 : bad outcome

Secondary

Measure	Time frame	Description
Neurologic outcome (Rankin)	30 day from in-ICU admission	Rankin score to assess neurologic outcome * 0-1-2 good outcome * 3-4-5 bad outcome
death	30 day form in-ICU admission	all-causes death

Contacts

Primary ContactBRUNO LEVY, MD-PHD

b.levy@chru-nancy.fr03 83 15 40 84

Outcome results