Progression
Conditions
Brief summary
A multiple-center study on the effect of different ways of lymph node dissection on the prognosis of less than 3cm ground glass nodules with more than solid components
Interventions
PROCEDURELymphadenectomy
Patients with ground glass nodules smaller than 3cm and with more than 50%solid components would randomly assigned to selective lymphadenectomy group or systematic lymph node dissection group
Sponsors
Shanghai Zhongshan Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
1. Aged between 18 and 75 years; 2. GGO is diagnosed by lung CT and failure to subside after 3 months (the patient having been re-examined by thin-section CT); 3. The maximum diameter of the GGO is smaller than 3cm; 4. The maximum diameter of the solid component in the GGO is more than 50%; 5. The patient is able to undergo the lobectomy 6. The patient is able to understand and comply with the study and has provided written informed consent.
Exclusion criteria
\- Patients meeting any of the following criteria are not eligible for this trial: 1. Patients with a history of using immunosuppressive or hormonal drugs; 2. Patients receiving radiotherapy or chemotherapy; 3. Patients who fail to comply with our follow-up strategy; 4. Other situations that are not in conformity with the standards and requirements of this trial.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| overall survival (OS) | 5 years | five year overall survival |
Countries
China
Contacts
Primary ContactJiang Wei, Dr
Outcome results
None listed