The Effect of Frailty and Other Geriatric Syndromes on the Prognosis of Elderly Patients With Acute Coronary Syndrome

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04580706

Enrollment

1000

Registered

2020-10-08

Start date

2020-01-01

Completion date

2021-12-31

Last updated

2020-10-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ACS, Elderly Patient, Frail Elderly Syndrome

Brief summary

This is a prospective observational clinical trail which will recruit 1000-1500 participants over 65 years with frailty and acute coronary syndrome (ACS) in Beijing Friendship hospital. The investigators will conduct frailty assessment (FRAIL scale, CFS, SPPB), comorbidities, functional status (Barthel index, ADL, IADL), nutritional risk (MNA-SF), and then observe the clinical outcomes of elderly ACS participants with frailty. Then, the investigators will follow-up these participants separately in 1,3,6 and 12months, the anticipate follow-up time is 1 year. According to the follow-up results, investigators will evaluate the impact of frailty and other senile syndromes on the short-term and long-term prognosis of ACS, and develop a scoring system for the prognosis evaluation of elderly ACS participants.

Interventions

OTHERthis is an observational study with none intervention

this is an observational study with none intervention

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

* Elderly participants over 65 * Clinical diagnosis of acute coronary syndrome * Must be able to follow-up * Sign in the informed consent

Exclusion criteria

* Myocardial infarction caused by other acute disease * Mental disorders who cannot cooperate to complete the assessment * Severe liver dysfunction, kidney disease (CKD 5), end-stage malignant tumor * Totally disabled and bedridden

Design outcomes

Primary

Measure	Time frame	Description
Death	During hospitalization, assessed up to 2 months	All-cause death and cardiac death events
Major Adverse Cardiac and Cerebrovascular events	During hospitalization, assessed up to 2 months	Major Adverse Cardiac and Cerebrovascular events including heart failure, cardiac shock, malignant arrhythmia, myocardial infarction, revascularization, and cerebral infarction

Countries

China

Contacts

Primary ContactSun Ying, MD

sunying@bfh.com.cn010-63137726

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026