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The Optimization of Medications in Chronic Heart Failure Using a Website

The Optimization of Medications in Chronic Heart Failure Using a Website

Status
Terminated
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04580004
Enrollment
3
Registered
2020-10-08
Start date
2020-09-24
Completion date
2021-02-08
Last updated
2022-02-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Failure

Brief summary

Heart failure (HF) is the most common hospital discharge diagnosis among older adults in the United States. Strikingly, 2 in 5 patients are readmitted within 1-year following their first HF admission. This results in significant potentially avoidable costs to our already strained healthcare system since hospitalizations result in 70% of yearly HF management costs. One of the most common causes of readmission is lack of medication optimization. This study will determine the effectiveness of a medication optimization website.

Detailed description

In a prospective design, 100 patients will be randomized to the intervention or usual care in a 1:1 fashion. Patients randomized to the intervention will receive an evidence-based medication recommendation intervention. Outcome measures will be collected at baseline and at 2 weeks post-intervention.

Interventions

OTHERMed Optimization Arm

An evidence-based medication recommendation website that is provided to the patients.

Sponsors

University of Michigan
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* left ventricular ejection fraction (LVEF) \</= 40%

Exclusion criteria

* pregnancy * active cancer with a life expectancy less than 12 months * hospice * chronic inotropic therapy

Design outcomes

Primary

MeasureTime frameDescription
The change in medications will be measured by the Evidence Based Medicine Percent Score (EBMPS).Change over 2 weeksThe Evidence Based Medicine Percent Score (EBMPS) is calculated by the medications and doses the patient is taking (in points) divided by the total eligible medications based on the evidence (in points).

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026