Ocular Illness, Visual Impairment
Conditions
Brief summary
This project will apply non-invasive, trans-cutaneous vagal nerve stimulation using various stimulation parameters to young, healthy adults to find the optimal set of parameters to elicit pupil response.
Interventions
DEVICEtranscutaneous electrical nerve stimulation devices
electrical stimulation through surface electrodes
Sponsors
University of Florida
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
This study has a within-subjects design with a randomization of the order of tVNS administered parameters
Eligibility
Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Fluent English speaker with reading and writing proficiency.
Exclusion criteria
* Participants with significant visual impairment or ocular illness may be excluded at the discretion of the principal investigator. * Major medical illnesses including severe neurological illness (e.g. stroke, seizure history), autoimmune disorders, and severe psychiatric diseases (e.g., schizophrenia) * Any history of brain surgery, tumor, intracranial metal implantation, pacemakers, or other implanted devices. * Current (i.e. within 48 hours of the session) prescription medication or over-the-counter medication use. * Illicit alcohol or drug use. Caffeine (e.g, coffee, energy drinks) consumption prior to the visit.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Ocular response after transcutaneous nerve stimulation | Visit 1 day | Number of participants with pupil response after transcutaneous nerve stimulation |
Countries
United States
Outcome results
None listed