Skip to content

Development and Evaluation of Techniques for Computer Aided Detection and Diagnosis From Existing Radiologic Images

Development and Evaluation of Techniques for Computer Aided Detection and Diagnosis From Existing Radiologic Images

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04579237
Enrollment
144625
Registered
2020-10-08
Start date
2020-10-05
Completion date
2030-06-30
Last updated
2025-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Radiology Information Systems

Keywords

Opportunistic screening, Artificial Intelligence, Automated Detection, Epidural Masses, Lymphadenopathy, Natural History

Brief summary

Background: Radiologic images are getting more complex. They are also being used more often. Medical personnel are overwhelmed with data. Computer Aided Detection (CAD) and diagnosis may be able to improve medical care. Researchers want to create and test ways to use CAD. To do this, they want to use data from the Clinical Center s Department of Diagnostic Radiology. Objective: To create algorithms and software that accurately detect and characterize lesions, model anatomy, and monitor diseases on radiologic studies. Eligibility: People of all ages who have radiologic exams stored in the clinical PACS (picture archiving system) of the Clinical Center since July 6, 1953 with no end date. People with target lesions of any kind will be included. Design: This study will use existing data. Participants will include males and females of all ages. They will be chosen by keyword search on NIH databases. The data that is used may include CT, MRI, ultrasound, and other images. It may include a participant s name, date of birth, and date of exam. It may include the name of the doctor, radiologist, and hospital. Data such as age, gender, race, disease, and treatment may be used. Other data from charts or studies may be used. Imaging data of all organs of the body will be studied. Data will be kept in computers and servers. The equipment will be password protected. Printouts will be stored in locked rooms. This study will last 10 years.

Detailed description

Study Description: This study uses artificial intelligence techniques to improve radiology diagnosis. Objective: Development of Computer Aided Detection techniques to improve radiology imaging. Study Population: Up to 1,000,000 NIH Clinical Center patients. Description of Sites/Facilities conducting research: NIH Clinical Center Study Duration: 10 years

Interventions

None listed

Sponsors

National Institutes of Health Clinical Center (CC)
Lead SponsorNIH

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
1 Years to 100 Years
Healthy volunteers
No

Inclusion criteria

* INCLUSION CRITERIA: * All radiologic exams available in the clinical PACS (picture archiving system) of the Clinical Center taken from July, 6, 1953 with no end date. * Males and Females of all ages. * Patients with target lesions of any kind will be included * Patients without the target lesion will be included to determine the specificity of the computer aided detection or diagnosis algorithm

Exclusion criteria

None

Design outcomes

Primary

MeasureTime frameDescription
Development of Computer Aided Detection techniques to improve radiology imagingEnd of studyDevelopment of Computer Aided Detection techniques to improve radiology imaging

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026