Premature Coronary Heart Disease
Conditions
Keywords
Premature coronary heart disease, Degree of coronary stenosis, arterial stiffness
Brief summary
Premature coronary heart disease (CHD) refers to the onset of myocardial infarction in men \< 55 years old, women \< 65 years old. At present, researches on early-onset coronary heart disease mostly focus on its risk factors and clinical characteristics, but there is no relevant research on the relationship between early-onset myocardial infarction and atherosclerosis.
Detailed description
Premature coronary heart disease is defined as the first onset of male \< 55 years old, female \< 65 years old, confirmed by clinical examination. A number of studies have found that smokers have a significantly increased risk of acute myocardial infarction, and suggest that continued smoking is still an independent predictor of mace. These findings suggest that smoking is significantly associated with early-onset coronary heart disease. A number of studies have found that smoking can increase peripheral arterial stiffness. At present, there is no study on peripheral arterial stiffness in patients with early-onset myocardial infarction, so we suspect that peripheral arterial stiffness in patients with early-onset myocardial infarction is significantly increased
Interventions
None listed
Sponsors
Chongqing Medical University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* The onset of coronary heart disease (including acute coronary syndrome and stable angina pectoris) was less than 55 years old in men and 65 years in women
Exclusion criteria
* Non coronary heart disease leading to chest pain (myocarditis, pericarditis, pulmonary embolism, aortic dissection, unstable angina pectoris) definite infection tumor liver and kidney insufficiency autoimmune disease acromegaly hyperthyroidism and subclinical hyperthyroidism secondary hypertension, etc.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Arterial stiffness | On admission | The arterial stiffness of HFpEF patients, for exampleambulatory arterial stiffness indexbrachial ankle pulse wave velocity, ardioankle vascular index and so on. |
| Degree of coronary stenosis | On admission | Degree of coronary stenosis indicated by coronary angiography |
Countries
China
Contacts
Primary ContactDongying Zhang, doctor
Outcome results
None listed