Multiple Rib Fractures, Pain, Acute, Serratus Anterior Plane Block
Conditions
Keywords
serratus anterior plane block, multiple rib fractures
Brief summary
The present clinical study will be undertaken to evaluate the effect of Ultrasound-guided Deep versus Superficial continuous Serratus Anterior Plane Block for pain management in patients with multiple rib fractures.
Detailed description
Thoracic blunt trauma, especially when multiple rib fractures are associated, is challenging to manage and causes significant morbidity due to the severe pain implied. Patients can present with respiratory compromise as their capacity to expand the thorax is limited by pain. As a result, they are at high risk to develop atelectasis and pneumonia. the key goal of management is adequate analgesia and pulmonary volume expansion Various strategies to treat such pain have been utilized, including regional analgesia (intrapleural, intercostal paravertebral nerve blockade), and neuraxial analgesia (thoracic epidural analgesia (TEA), intrathecal opioids). The use of neuraxial analgesia in polytrauma is frequently limited by the need for aggressive venous thromboembolic (VTE) prophylaxis, and positioning of the patient for a neuraxial approach may be impossible. There is a growing interest in exploring treatments that are less invasive than EA and can be performed on patients who have contraindications to neuraxial analgesia. Ultrasound-guided Serratus Anterior Plane (SAP) block is a recent technique, first described by Blanco et al. in 2013, that provides analgesia for the thoracic wall by blocking the lateral branches of the intercostal nerves from T2 to L2. It is a safe, simple to perform block with no significant contraindications or side effects. he described 2 potential spaces, one superficial and another deep to serratus. The SAPB has been used effectively for the management of pain in the context of rib fractures, thoracoscopic surgery, thoracotomy, breast surgery, and post-mastectomy pain syndrome, few studies compared the two approaches, and the difference between them has not yet been studied in patients with multiple rib fractures.
Interventions
Local anesthetic infusion though a peripheral nerve catheter placed related to the serratus anterior muscle at the level of the 5th rib
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Masking description
neither the patient or the investigator included in data collection will be aware of the type of block performed or the group allocation
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Adult patients of either sex, having three or more unilateral fracture ribs and admitted to the trauma ICU, Rib fractures were confirmed by X-ray and CT scan reads.
Exclusion criteria
* significant head injury and unconsciousness (GCS less than 14) * Patients with significant pain from other injuries * pathological obesity (body mass index ≥35) * history of drug allergy local anesthetics * local infection at the injection site * inability to obtain consent from patient or surrogate, and patient refusal
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in pain score | before and after the block at 30 minutes, 2hours, 4hours, 6hours, 12hours, 24hours, 36hours, 48 hours & 72hours | patient report numerical rating scale (NRS) 0 to 10, with 0 being no pain and 10 being the worst pain imaginable |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| change in Serum beta-endorphin level | before procedure and at 24 hours post procedure | We will use radioimmunoassays to measure plasma beta-endorphin level |
| Lung Ultrasound Score (LUSS) | before and after block at 90 minutes then every 24 hours for 3 days | We will use a techniques based on the international evidence-based recommendations for point-of-care lung ultrasound that recommended using a complete eight-zone lung ultrasound ,The worst ultrasound pattern observed in each zone was recorded and used to calculate the sum of the scores (total score = 24). |
| Change in inspiratory volumes (mL) | before and after block at 90 minutes then every 12hours for 3 days | Maximum inspiratory respiratory volume (measured in ml) recorded on single use of incentive spirometer device |
| heart rate | before and after the block every 2hours for 3 days | heart rate by EKG monitor |
| peripheral arterial oxygen saturation (SpO2) | before and after the block every 2hours for 3 days | measured by Pulse oximetry |
| mean arterial blood pressure | before and after the block every 2hours for 3 days | mean arterial blood pressure by non invaisive blood pressure monitoring |
Countries
Egypt
Outcome results
None listed