MSSA and MRSA Screening in Patients Undergoing Elective TJA: the Benefits of Next-generation Sequencing

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04574752

Enrollment

163

Registered

2020-10-05

Start date

2020-08-30

Completion date

2021-08-30

Last updated

2020-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Next Generation Sequencing, Staphylococcus Aureus, Total Joint Arthroplasty

Brief summary

The aims of this study were to evaluate the diagnostic performance of molecular and culture techniques in S. aureus screening using paired nasal and groin swabs, to determine, if any, discrepancy between the diagnostic techniques and to model the potential effect of different diagnostic techniques on S. aureus detection in orthopaedic patients

Interventions

DIAGNOSTIC_TESTnext generation sequencing

diagnostic performance of molecular and culture techniques in S. aureus screening using paired nasal and groin swabs, to determine, if any, discrepancy between the diagnostic techniques on S. aureus detection in orthopaedic patients

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* All patients undergoing primary total knee or total hip arthroplasty at our institution will be eligible.

Exclusion criteria

* Patients included in other prospective studies

Design outcomes

Primary

Measure	Time frame	Description
Diagnostic techniques to identify S. aureus in total joint replacement patients	1 day	to model the potential effect of different diagnostic techniques on S. aureus detection in orthopaedic patients.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026