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Does the Air-bubble Location Influence on the Implantation Rate

Evaluation of the Implantation Rate Depending on the Air Bubble Location Through Ultrasound Into the Uterine Cavity in Pre-embryo Transfer

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04574310
Acronym
TRANSFER
Enrollment
400
Registered
2020-10-05
Start date
2013-09-20
Completion date
2019-10-25
Last updated
2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Embryo Disorder

Keywords

embryo, pregnancy

Brief summary

The main objective of the study is to evaluate whether there is any association between the location into the uterine cavity, where the air bubbles containing the pre-embryos were placed, and the implantation rate. Therefore, the images generated during pre-embryos transfer are available in our database and studied retrospectively.

Detailed description

The success of a reproductive treatment is determined by three variables: the pre-embryo quality, endometrial receptiveness and pre-embryo transfer. Several previous studies show a lack of agreement concerning the greatest measurement. For instance, some of them refer to the distance between the catheter and the uterine fundus, whereas some others take as a reference the air-bubble where the pre-embryos were placed. It is for this reason that in the present study, we aim to evaluate the air bubble location ratio into the uterine cavity with reproductive success, taking into account the different variables to reach success. That is, embryo characteristics (quality, development day) endometrium preparation (cycle type, hormone levels on day 5) and even the transfer procedure (type of catheter, blood, difficulty channeling). It is a study that aims to collect data from January 2013 to october 2019. To this end, the images generated during pre-embryos transfer are analyzed retrospectively. Therefore, it is evaluated the existing differences on implantation rate according to air-bubble placement into uterine cavity during the transfer procedure.

Interventions

OTHERCollect retrospectively data on embryo implantation rate

Collect retrospectively data on embryo implantation rate

Sponsors

IVI Vigo
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
30 Years to 50 Years

Inclusion criteria

* Patients with normal uterine anatomy, who underwent an ultrasound guided embryo transfer. * BMI\< 30kg/m2. * Ultrasound guided embryo transfer made by the same researcher.

Exclusion criteria

* Presence of uterine fibroid in the anterior uterine body that make difficult the transfer visualization. * Asherman Syndrome. * Adenomyosis that reduces the uterine cavity visibility. * Difficult transfers where the use of a semi-rigid cannula sheath is needed to entry into the uterine cavity. * Previous uterine surgery that alters its anatomy. * Istmocele

Design outcomes

Primary

MeasureTime frameDescription
Implantation rateSince September 2013 October 2019Analyze Implantation rate in the groups

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026