Regional Anesthesia in THR - Comparing the Analgesic Efficacy of Fascia Iliaca Block and Erector Spinae Plane Block

Regional Anesthesia in THR - Comparing Analgesic Efficacy of Fascia Iliaca Block and Erector Spinae Plane Block

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04574154

Acronym

PTA-ALR

Enrollment

Registered

2020-10-05

Start date

2020-01-20

Completion date

2021-08-21

Last updated

2021-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Brief summary

THR (Total Hip Replacement) can be very painful and regional anesthesia is very effective in reducing postoperative pain. Fascia Iliaca Block (FIB) and Erector Spinae Plane Block (ESPB) are indirect approaches to the lumbar plexus that resulted to be very promising for THR. However, no studies investigated the analgesic superiority of either FIB or ESPB. In our study the investigators compare FIB and ESPB in terms of pain relief expressed as morphine consumption in the first 24 hours after primary THR.

Interventions

PROCEDUREESPB

ESPB (L4) with ultrasound: Ropivacaine 0.5% 40 ml

PROCEDUREFIB

FIB with ultrasound: Ropivacaine 0.5% 40 ml

PROCEDUREspinal anesthesia

bupivacaine 0,5% 2.2 ml

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Intervention model description

randomized trial

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* primary THR * informed consent

Exclusion criteria

* allergies to study drugs * spinal anesthesia contraindicated * kidney failure * epilepsy, psychiatric disease, neurologic deficits * revision surgery * neuropathies in the lumbar area * no informed consent * pregnancy * alcohol/opioid abuse * emergency surgery/intensive care

Design outcomes

Primary

Measure	Time frame	Description
morphine	24 hours	milligrams of morphine consumed in the first postoperative day

Secondary

Measure	Time frame	Description
perceived postoperative pain: Numeric Rating Scale (NRS)	24 hs	11 point scale from 0 = no pain to 10 = worst imaginable pain
side effects	48 hours	occurrence of nausea/vomiting, ileum, pruritus and urinary retention in the first 48 hours

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026