Motor Recovery, Repetitive Transcranial Magnetic Stimulation, rTMS, Stroke
Conditions
Brief summary
This study is based on the characteristics of motor learning theory and motor learning neural network to improve motor function in stroke patients. This study is to investigate whether the cerebral-cerebellar repetitive transcranial magnetic stimulation (rTMS) is effective in improving motor function compared to the conventional cerebral rTMS in stroke patients.
Interventions
PROCEDURERepetitive transcranial magnetic stimulation
rTMS over cerebral motor cortex and cerebellar hemisphere
Sponsors
Samsung Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Hemiplegic stroke patients within 1 month after onset * Moderate to severe motor impairment (Fugl-Meyer assessment \<85) * Cognitive and language functions to perform more than one step of command * More than 19 years old
Exclusion criteria
* Contraindicated to rTMS * Progressive or unstable stroke * Pre-existing and active major neurological disease or major psychiatric disease * A history of advanced liver, kidney, cardiac or pulmonary disease, a terminal medical diagnosis consistent with survival \<1 year
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Difference of upper limb motor score in Fugl-Meyer assessment | 2 weeks | (upper limb motor score in Fugl-Meyer assessment at post-intervention) - (upper limb motor score in Fugl-Meyer assessment at baseline) Higher scores mean a better outcome |
Countries
South Korea
Outcome results
None listed