Vitreous Anomalies, Vitreous Disorder
Conditions
Brief summary
To measure vitreous collagen fragments length after pars plana vitrectomy performed at different cut rates
Detailed description
Pars plana vitrectomy consists in the removal of vitreous obtained with a vitreous cutter. The instruments attracts vitreous in its port through active suction and cuts with a blade at different cut rates. There is no consensus as to which cut rate would be ideal in order to minimize traction, neither there is agreement on whether increasing cut rates generate shorter collagen fragments or the fluid turbulence creates unpredictable flows at the port generating fragments of different length. The investigators plan to gather vitreous cut at 1,000, 2,000, 4,000, 8,000 and 16,000 cuts per minute and measure vitreous collagen average length
Interventions
removal of vitreous with vitreous cutter
Sponsors
Study design
Eligibility
Inclusion criteria
* patient undergoing pars plana vitrectomy for: * macular pucker * macular hole- * retinal detachment * age \>18
Exclusion criteria
* unwilling to participate * previous trauma * vitreous haemorrhage
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| collagen fragment molecular weigth | at time of surgery | collagen passed through the vitreous cutter is examined with regard to collagen moecular weigth |
Countries
Italy