Cataract, Endophthalmitis
Conditions
Keywords
Ocular/Eyelid Flora
Brief summary
Antibiotics are commonly utilized to reduce the bacterial population of the eye prior to surgery with the assumption that this reduces the risk of endophthalmitis, although it is not clear if this actually occurs. This study will investigate the use of Hypochlorous Acid, a commercially available over the counter (OTC) medication to see if this will reduce the bacterial population prior the cataract surgery.
Interventions
DRUGHypochlorous Acid Gel 0.02%
0.02% Hypochlorous Acid Gel (OCusoft Hypochlor GEL) will be sprayed onto the closed eyelid of the surgical eye while covering the fellow eye with palm of the hand, left for 60 seconds, then wiped off with a clean gauze, tissue, or cotton ball.
Sponsors
Loma Linda University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 95 Years
Healthy volunteers
No
Inclusion criteria
\- Patients undergoing cataract surgery.
Exclusion criteria
* Age \<18 years old * Vulnerable subjects * Non-English Speakers
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Reduction in bacterial flora in eyelashes of treatment eye compared to fellow eye | On day of surgery prior to surgical prep | Swab will be used to obtain samples from the eyelashes bilaterally and cultured |
| Reduction in bacterial flora in conjunctiva of treatment eye compared to fellow | On day of surgery prior to surgical prep | Swab will be used to obtain samples from the conjunctiva bilaterally and cultured |
Countries
United States
Outcome results
None listed