Postoperative Nutrition
Conditions
Brief summary
Introduction: Nutritional support is a vital therapy of most surgical patients. Early initiation via the enteral route has a significant effect on postoperative recovery. The prognostic role of CRP and albumin can be explained by their abilities to reflect inflammation in the acute phase in critical settings and assess the nutritional status of critically ill patients, respectively. This indicates the prognostic value of the CRP/ALB ratio in postoperative patients admitted to the ICU. Aim of work: Determine the effect of early enteral & parenteral nutrition on ICU outcome & nutritional status in postoperative abdominal surgical patients and investigate the effect of enteral & parenteral nutrition on CRP/albumin ratio as an inflammatory marker & its correlation with SOFA score. Methods: A prospective cohort non randomized study included 80 postoperative abdominal surgical patients at Critical Care Department, Cairo University over one year duration. Forty patients (50%) received enteral nutrition 6 hours after surgical procedures and 40 patients (50%) received parenteral nutrition 6 hours after surgical procedures. Nutritional status and inflammatory markers were screened. All patients were followed up during the ICU stay & up to 3 months. SOFA scoring was done every 48 hours.
Interventions
DIETARY_SUPPLEMENTpostoperative nutrition
Forty patients (50%) received enteral nutrition 6 hours after surgical procedures and 40 patients (50%) received parenteral nutrition 6 hours after surgical procedures.
Sponsors
Cairo University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* postoperative abdominal surgical patients at Critical Care Department, Cairo University over one year duration. * age between 18-80 years
Exclusion criteria
* renal failure * liver failure * extensive burns * hemodynamic instability.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Gastro-intestinal tolerance: vomitting or diarrhea | 7 days | number of participants who develop nausea, vomitting or diarrhea |
| Refeeding syndrome; hypokalemia and hypophosphatemia | 7 days | number of participants who develop hypokalemia and hypophosphatemia |
| length of ICU stay | 7 days | measurement of days of ICU stay |
| duration of mechanical ventilation. | 7 days | measurement of days of mechanical ventilation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 3 months survival after discharge . | 90 days | measurement of the rate of survival within 3 months between participants |
| re-admission within 30 days | 30 days | measurement of the rate of hospital re-admission within 30 days between participants |
Outcome results
None listed