Ventilator Associated Pneumonia
Conditions
Brief summary
Ventilator Associated pneumonia (VAP) is associated with longer ICU length of stay, prolonged mechanical ventilation, and increased use of antimicrobials, health-care cost and mortality . Acute respiratory infections (ARIs) comprise a large and heterogeneous group of infections, including bacterial infections, viral infections, and infections of other etiologies. Early initiation of adequate antibiotic therapy is the cornerstone in the treatment. However, overuse of antibiotics and prolonged duration of antibiotic therapy in patients with bacterial ARIs in the hospital and intensive care setting is associated with increased resistance for common bacteria, high costs, and adverse drug reactions.
Interventions
DIAGNOSTIC_TESTLung Ultrasound
We will evaluate the role of lung ultrasound on the duration of antibiotics, we hypothesize that ultrasound imaging may have a role, will be correlated with, procalcitonin (PCT). The created database will help in establishing conclusion and recommendations that will help to improve the antibiotics duration and decrease the resistance.
Sponsors
Ain Shams University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* 18 years old or greater * Ventilator associated pneumonia (VAP) with positive sputum culture.
Exclusion criteria
* pregnancy, * use of immunosuppressive agents except for steroids, * neutropenia (white blood cell count ≤1000/mL) * patients whose primary diagnosis was community acquired pneumonia and other source of infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| correlation between lung ultrasound and procalcitonin. | 7 days |
Countries
Egypt
Outcome results
None listed