Hemodialysis Complication
Conditions
Brief summary
Xerostomia is a subjective complaint of dry mouth, whereas hyposalivation is an objective decreased of salivary flow. Hyposalivation was reported in 28.8 % of haemodialysis (HD) patients (Bruzda-Zwiech, 2014).
Detailed description
Stimulation of the salivary glands can be induced mechanically (for example, by chewing gum or acupressure) or through medications (such as pilocarpine, cevimeline, angiotensin-converting-enzyme inhibitors and angiotensin-receptor blockers) or by electrostimulation as transcutnaeous electrical nerve stimulation (TENS) (Bossola and Tazza, 2012). Eighty HD patients (40 diabetics and 40 nondiabetics) will receive 20 minutes of TENS on skin over bilateral parotid gland, 3 times weekly for 3 weeks to investigate the hyposalivation response of diabetic and non diabetic HD patients to TENS.
Interventions
DEVICETENS
Patients of this group will receive 20 minutes of extra oral TENS over skin of bilateral parotid glands (3 sessions weekly for 3 weeks)
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
30 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Eighty HD patients (40 diabetics and 40 non diabetics) * HD at least from three month * saliva flow less than or equal 0.15 millilitre per minute
Exclusion criteria
* pulmonary or cardiac disorders * drugs to treat hyposalivation * salivary glands inflammation, tumor, and autoimmune diseases. * smokers and alcholics
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 3-week response of salivary flow rate | immediately after the last session | the patients will be ordered to spit saliva in a graduated test tube for 5 minutes after the last session (session number 9). To calculate salivary flow rate: saliva volume will be divided on duration of saliva spitting. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| immediate response of saliva flow | immediately after the first session | the patients will be ordered to spit saliva in a graduated test tube for 5 minutes immediately after the first session . To calculate salivary flow rate: saliva volume will be divided on duration of saliva spitting. |
Countries
Egypt
Contacts
Primary ContactAli Ismail, lecturer
Outcome results
None listed