Success of Inferior Alveolar Nerve Block
Conditions
Brief summary
the study is conducted to assess the effect of adding magnesium sulphate to mepivacaine HCl compared to mepivacaine HCl alone on the success of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis in mandibular molars
Interventions
DRUGMagnesium sulfate
patients will be given an IANB injection by adding 0.18 mL of 10% magnesium sulphate to 1.8 ml of 2% mepivacaine HCL with Levonordefrin HCl 1:20000/ 1.8 ml , after withdrawal of 0.18ml from the local anesthetic carpule by using a 100 IU insulin syringe
DRUGMepivacaine-Levonordefrin Hydrochloride
patients will be given an IANB injection by adding 0.18 mL of sterile distilled water to 1.8 ml of 2% mepivacaine HCL with Levonordefrin HCl 1:20000/ 1.8 ml , after withdrawal of 0.18ml from the local anesthetic carpule by using a 100 IU insulin syringe
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
1. Age between 18-55 years old. 2. Systemically healthy patient (ASA I or II). 3. Mandibular molar teeth with: * Preoperative sharp pain. * No widening in the periodontal ligament (PDL). * Vital response of pulp tissue to cold pulp tester (ethyl chloride spray)1. * Fully formed roots. 4. Positive patient's acceptance for participation in the study.
Exclusion criteria
1. Patients who had used any type of analgesic medication during the preceding 12 hours before the treatment. 2. Pregnant or nursing females. 3. Patients having significant systemic disorder (ASA III or IV). 4. Drug abusers and subjects who were on antidepressant medication. 5. Re-treatment cases. 6. Patients with a contraindication for the use of magnesium sulphate or those known to be allergic to any of the study medications.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| success of inferior alveolar nerve block measured using a numerical rating scale (NRS) | 15 minutes after injection | Intensity of pain 15 minutes after injection during access cavity and initial file placement is recorded by the patient using a numerical rating scale(where 0= no pain ,1-3 =mild pain ,4-6= moderate pain and 7-9= severe pain ) |
Contacts
Primary Contactalaa Ib mekhimar, B.D.S
Outcome results
None listed