NAFLD, NASH - Nonalcoholic Steatohepatitis
Conditions
Keywords
Egyptian population, NAFLD, NASH, DNA extraction, liver enzymes
Brief summary
Due to the limited data concerning Egyptian population. authors aimed to investigate the differentadipokine gene polymorphism related to non alcoholic fatty liver disease incidence, prognosis and progression to steotosis and also to find different related factors including obesitu, diabetes and liver enzymes level
Interventions
GENETICDNA extraction
investigation of DNA polymorphism in patients suffering from NAFLD
Sponsors
Elsahel teaching hospital
Cairo University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Inclusion criteria
Egyptian patients confirmed NAFLD diagnosis diabetic \-
Exclusion criteria
* Pregnancy and lactation, history of alcohol abuse (as defined by an average daily consumption of alcohol \> 30 g/day in men and \> 20 g/day women), cirrhosis, autoimmune hepatitis and other causes of liver disease (viral hepatitis, hemochromatosis, Wilson's disease), drug induced hepatitis, chronic enteropathies, Chronic kidney disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| investigate adipokine dna polymorphism | 1 months | to investigate adipokine gene polymorphism associated with prognosis of NAFLD patients |
| correlations | 1 month | to correlate between gene polymorphism and glycated hemoglobin, liver enzyme and obesity |
Countries
Egypt
Outcome results
None listed