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Diagnosing Acute Onset Insufficient Intestinal Blood Flow (Bowel Ischemia) With a Novel CT Technique Called Dual-energy CT (DECT). This Observational Study Seeks to Evaluate Whether DECT Can Improve the Diagnosis of Bowel Ischemia and How the DECT Findings Correlate With Intraoperative Findings

Dual-energy CT in the Diagnosis of All-Cause Acute Bowel Ischemia

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04561323
Enrollment
44
Registered
2020-09-23
Start date
2020-11-01
Completion date
2022-04-01
Last updated
2021-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Bowel Ischemia / Infarction, Bowel Ischemia

Keywords

Dual-energy CT

Brief summary

The aim of this study is to evaluate the performance of dual-energy CT (DECT) in the diagnosis of acute bowel ischemia (ABI). ABI is a condition characterised by inadequate blood supply to portions of the intestine. ABI is a relatively rare condition, but is associated with a high mortality rate. DECT is an emerging field within radiology. Few reports have reported an increased conspicuity for ABI using DECT compared with conventional CT, which is the current preoperative golden standard. The investigators hypothesize that DECT increases conspicuity of ABI compared with conventional CT and that DECT image findings correlate with the intraoperative findings.

Interventions

DIAGNOSTIC_TESTDual-energy CT

Patients suspected of acute bowel ischemia will be scanned in the dual-energy CT scanner. The abdominal imaging protocols are predetermined by the Department of Diagnostic Radiology, Righospitalet, Denmark.

Sponsors

Rigshospitalet, Denmark
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Referred on the suspicion of acute bowel ischemia

Exclusion criteria

* Patient not scanned with DECT * Patient does not undergo abdominal surgery

Design outcomes

Primary

MeasureTime frame
Adding DECT information increases assessor confidence without lowering the specificity compared with standard CT in the diagnosis and/or exclusion of ABI.10 minutes

Secondary

MeasureTime frame
Intraoperative ICG fluorescence angiogram perfusion assessment and its correlation to DECT image evaluation.10 minutes

Countries

Denmark

Contacts

Primary ContactJack J Xu, MD
jack.junchi.xu@regionh.dk+4525122159

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026