Covid19
Conditions
Keywords
elderly, coronavirus disease
Brief summary
Statement : * The emerging Coronavirus 2019 (COVID-19) disease, linked to the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pathogen, has been spreading worldwide since December 2019, affecting millions of people and causing hundreds of thousands of deaths, particularly among the elderly. * The first epidemiological evidence available reveals a different expression of the disease in the elderly, associated with a high risk of delayed diagnosis and implementation of protective measures and a particularly high morbidity and mortality, especially among the frailest. * To date, there is no effective model for predicting the severity of COVID-19 in an individual. The investigators hypothesize that there are specificities of COVID-19 in the elderly, both etiological, diagnostic and prognostic, all of which are not yet known and understood.
Interventions
None listed
Sponsors
University Hospital, Angers
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
70 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Hospitalization in the Geriatric unit of the University Hospital (UH) of Angers from 15/03/2020 and until the closure of the COVID-19 geriatric sector
Exclusion criteria
* Opposition to the use of the information collected for research purposes.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diagnosis of COVID-19 | baseline | Recovery of the diagnosis method (PCR or thoracic scan) |
| Length of hospitalization | at the 3-month follow-up | — |
| Medical history and co-morbidities | baseline | listing of medical history and co-morbidities data provided by the physician and the family during hospitalization |
| The physical examination data, and reports of relevant investigations data provided by the physician and the family during hospitalization | baseline | The demographic characteristics are age, sex, marital status, place of life, career, presence of un/formal assistance, … |
| Electrocardiography QT Interval | baseline | all electrocardiograms performed during hospitalization |
| Number of different therapeutic classes | baseline | Number of different therapeutic classes taken per day. |
| Comprehensive Geriatric Assessment (CGA) | baseline | Comprehensive geriatric assessment (CGA) is defined as a multidisciplinary diagnostic and treatment process that identifies medical, psychosocial, and functional capabilities of an older adult in order to develop a coordinated plan to maximize overall health with aging. CGA is based on the premise that a systematic evaluation of frail older persons by a team of health professionals may identify a variety of treatable health problems and lead to better health outcomes. |
| Biological parameters | baseline | Characterization of the COVID-19 impact on the biological parameters evaluated by blood test. |
| Medical imaging results | baseline | Assessment of lesion extension (percent) with medical imaging results (thoracic scan) |
| Number of death from any cause | at the 3-month follow-up | — |
| Reports of relevant investigations data provided by the physician and the family during the two-month telephone follow-up | at the 3-month follow-up | The demographic characteristics are age, sex, marital status, place of life, career, presence of un/formal assistance, … |
Countries
France
Contacts
Primary ContactCédric ANNWEILER, MD, PhD
Outcome results
None listed