Excoriation (Skin-Picking) Disorder, Trichotillomania
Conditions
Brief summary
The primary aim of the study is to test the feasibility, safety and efficacy of a manual based, Internet-delivered, behavior therapy (I-BT) for trichotillomania and skin picking disorder.
Interventions
BEHAVIORALInternet delivered behavior therapy (I-BT)
10 weeks of I-BT
Sponsors
Region Stockholm
Karolinska Institutet
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Primary diagnosis of trichotillomania and/or skin picking disorder according to DSM-5 * Living in Sweden with a Swedish personal identification number * Able to participate in study assessment in Swedish and understand Swedish text * Have regular access to a computer with Internet access and skills to use Internet * Signed informed consent * Outpatient
Exclusion criteria
* Psychotropic medication changes that can affect symptoms of trichotillomania or skin picking disorder within 2 months prior to treatment * Other ongoing psychological treatments that could affect symptoms of trichotillomania or skin picking disorder * Completed CBT for trichotillomania or skin picking disorder within the last 24 months * Ongoing substance dependence or misuse * Lifetime bipolar disorder or psychosis * Suicidal ideation (a score of 5 points or higher on item 9 on the self-reported Montgomery-Åsberg depression rating scale * Psychiatric comorbidity that could severely jeopardize treatment participation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The Massachusetts General Hospital Hairpulling Scale | Change from baseline (week 0) to post-treatment (week 10), 1-, 3-, 6- and 12-month follow-up. | A self-report instrument for assessing repetitive hairpulling. The scale consists of seven items, rated for severity from 0 to 4 which assess urges to pull, actual pulling, perceived control, and associated distress. |
| The Skin Picking Scale - Revised | Change from baseline (week 0) to post-treatment (week 10), 1-, 3-, 6- and 12-month follow-up. | A 6-item self-report measure of skin picking disorder severity. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Acceptance and Action Questionnaire | Change from baseline (week 0) to post-treatment (week 10), 1-, 3-, 6- and 12-month follow-up. | Total scores on the scale range from 10 to 70 with higher scores indicating a worse outcome (decreased levels of accpetance). |
| Acceptance and Action Questionnaire for Trichotillomania | Change from baseline (week 0) to post-treatment (week 10), 1-, 3-, 6- and 12-month follow-up. | Total scores on the scale range from 9 to 63 with higher scores indicating a worse outcome (decreased levels of accpetance). |
| The Skin Picking Impact Scale | Change from baseline (week 0) to post-treatment (week 10), 1-, 3-, 6- and 12-month follow-up. | Total scores on the scale range from 0 to 50 with higher scores indicating a worse outcome (higher impact of skin picking). |
| The NIMH Trichotillomania Symptom Severity Scale | Change from baseline (week 0) to post-treatment (week 10) and 12-month follow-up. | Total scores on the scale range from 0 to 30 with higher scores indicating a worse outcome (higher symptom severity). |
| The NIMH Trichotillomania a Impairment Scale | Change from baseline (week 0) to post-treatment (week 10) and 12-month follow-up. | Total scores on the scale range from 0 to 10 with higher scores indicating a worse outcome (higher impairment). |
| Patient Health Questionnaire 9. | Change from baseline (week 0) to post-treatment (week 10) and 12-month follow-up. | Total scores on the scale range from 0 to 27 with higher scores indicating a worse outcome (more severe depressive symptoms). |
| EuroQol 5D, (EQ5D). | Change from baseline (week 0) to post-treatment (week 10) and 12-month follow-up. | The responses of the individual are weighted and calculated from 1 (full health) to 0 (death). The measure also includes a self-rated health scale, which ranges from 0 to 100, with higher scores indicating better self-rated health. |
| Montgomery Åsberg Depression Rating Scale Self Rate | Change from baseline (week 0) to post-treatment (week 10), 1-, 3-, 6- and 12-month follow-up. | Total scores on the scale range from 0 to 54 with higher scores indicating a worse outcome (more severe depressive symptoms). |
| Treatment credibility scale. | Scores at mid-treatment (week 5) and post-treatment (week 10). | The total score ranges from 1 to 10, with a higher score indicating a higher trust in the treatment. |
| Working Alliance Inventory - Short Form. | Scores at mid-treatment (week 5) and post-treatment (week 10). | The scale ranges from 12 to 84, with higher scores indicating a stronger working alliance. |
| Clinical global impression - severity scale. | Change from baseline (week 0) to post-treatment (week 10)] and 12-month follow-up. | Independent clinicians rate the severity of illness from normal (1) to extremely ill (7). |
| Clinical global impression - improvement scale. | Ratings at post-treatment (week 10) and at 12-month follow-up. | Independent clinicians rate the improvement from very much improved (1), to very much worse. |
| Global Assessment of functioning scale | Change from baseline (week 0) to post-treatment (week 10) and 12-month follow-up. | Independent clinicians rate the symptoms and their effect on functioning from 1 to 100. |
| Negative events questionnaire (NEQ). | Ratings at post-treatment (week 10). | The scale reports frequencies of negative events perceived by the participant as probably being caused by treatment and the negative impact of these events on a scale from 0 (not at all) to 4 (extreme). |
| Client Satisfaction Questionnaire-8. | Scores at post-treatment (week 10). | Total scores range from 8 to 32, with higher scores indicating greater satisfaction with a health care service. |
| Sheehan Disability Scale | Change from baseline (week 0) to post-treatment (week 10), 1-, 3-, 6- and 12-month follow-up. | Total scores on the scale range from 0 to 30 with higher scores indicating a worse outcome (higher degree of disability). |
Countries
Sweden
Outcome results
None listed