Myelopathy Cervical
Conditions
Brief summary
The objective of this study is to retrospectively analyze and compare the long-term clinical and radiographic results of multi-level laminoplasty to multi-level laminectomy and fusion for the treatment of patients with cervical myelopathy or myeloradiculopathy.
Interventions
PROCEDURECervical laminoplasty surgery
The posterior standard cervical laminoplasty procedure with ARCH mini-plate fixation
PROCEDURECervical laminectomy and fusion surgery
The posterior standard cervical laminectomy and fusion surgery procedure with lateral mass screws fixation
Sponsors
Shanghai Changzheng Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients aged at least 18 years * The patient has the diagnosis of degenerative cervical myelopathy * The myelopathy or myeloradiculopathy requires a posterior cervical decompression of the spinal canal involving two or more contiguous intervertebral levels including and between C3 and C7 * More than five years of follow-up time
Exclusion criteria
* Presence of primary focal anterior compression of the cervical spinal cord * Previous surgery of the cervical spine * Tumor, infection, or trauma of the cervical spine or cord * Patients with ankylosing spondylitis * Patients with neurodegenerative diseases, or any neuropathies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of Japanese Orthopaedic Association Score (JOA) | baseline, 12 months post-treatment and through study completion, an average of 10 year | Total score 0-17. The lower the score the more severe the deficits. |
| Change of Neck Disability Index (NDI) | baseline, 12 months post-treatment and through study completion, an average of 10 year | Ranging from 0%-100%. A higher score indicates more patient-rated disability. |
| Change of Sagittal Lordosis Angle | baseline, 12 months post-treatment and through study completion, an average of 10 year | Measured by lateral X-Ray image. The change of lordosis was calculated and compared. |
| Reoperation rate | through study completion, an average of 10 year | Any reoperation involving the same segments or adjacent segments will be calculated. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change of Range of Motion | baseline, 12 months post-treatment and through study completion, an average of 10 year | Measured by dynamic X-Ray image. |
| Complication rate | through study completion, an average of 10 year | Any complications related to surgery will be recorded. |
| Change of Pain Scores on the Visual Analog Scale (VAS) | baseline, 12 months post-treatment and through study completion, an average of 10 year | Ranging from 0-10. A higher score indicates more severe pain. |
Countries
China
Contacts
Primary ContactXuhua Lu, M.D.
Backup ContactBangke Zhang, M.D.
Outcome results
None listed