Age Problem
Conditions
Keywords
blood flow velocity, aging, respiratory pressure
Brief summary
The pourpose of this study is to verify if have relationship between respiratory muscle strenght, peripheral muscle blood flow and gait speed in the elderly.
Detailed description
The hypothesis of this study is that elderly with inspiratory muscle weakness will present lower peripheral blood flow and consequently lower walking speed. The main aim of the study is to verify if the peripheral muscular blood flow in the elderly is different between patients with and without decrease in inspiratory muscle strength. As secondary objectives, it will be evaluated the correlation between inspiratory muscle strength and gait speed and quality of life, as well as gait speed and peripheral muscle blood flow. Fifty elderly patients of both sexes, over 65 years, from Vila Mariana Einstein Outpatient Clinic and Cora Residencial Senior, will be included to evaluate Maximum Inspiratory Pressure (Pimáx), Maximum Expiratory Pressure (Pemáx), Spirometry (FVC, PF, FEV1), 4.6m Walk Test, Quality of life for the elderly (WHOQOL old), Mini Mental Test, Body Mass Index (BMI) and peripheral muscle blood flow by venous occlusion plethysmography.
Interventions
OTHERRespiratory muscle strength
Pimax and Pmax will be performed according to the (ATS) and (ERS). A Manovacuometer (Analog M 120, GlobalMed) with a range between 0-120cmH2O will be used. The elderly should undergo forced inspiration after maximal expiration and forced expiration after maximal inspiration through a mouthpiece with a hole to prevent closure of the glottis to evaluate Pimax and Pmax. The elderly should sustain the inspiration for 1 second. Three measurements will be performed, with a one-minute interval between them, with less difference equal to 10% between them, the higher value will be used.
Sponsors
Hospital Israelita Albert Einstein
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
65 Years to 100 Years
Healthy volunteers
Yes
Inclusion criteria
Elderly of both sexes, over 65 years old \-
Exclusion criteria
* Mini Mental Test \<24 * Morse ≥ 51 * Clinical instability, according to medical assessment • Structural heart disease, with ejection fraction \<50% and chronic lung diseases with FEV1 \<50% predicted, * Neurological, orthopedic, or neuromuscular diseases that prevent the performance of evaluations * Smokers or ex-smokers \<5 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Peripheral muscle blood flow, gait speed and handgrip strength | Day 1 | Check if there is a correlation between peripheral muscle blood flow, gait speed and handgrip strength and if this association is mediated by inspiratory muscle strength. |
Countries
Brazil
Contacts
Primary ContactLuciana D Matos, doctor
Backup ContactLetícia H Harada, specialist
Outcome results
None listed