Hepatectomy, Lobectomy, Pancreaticoduodenectomy
Conditions
Keywords
Maintenance Wakefulness Tests, micro-sleep, sleepiness, latency, EEG
Brief summary
During general anesthesia, intraoperative hypotension (IOH) is associated with increased morbidity and mortality. Mean arterial pressure (MAP) \< 65mmHg is the most common definition of hypotension. In order to reduce IOH, a complex method using machine learning called hypotensive prediction index (HPI) was shown to be superior to changes in MAP (ΔMAP) to predict hypotension (MAP between 65 and 75 excluded). Linear extrapolation of MAP (LepMAP) is also very simple and could be a better approach than ΔMAP. The main objective of the present study was to investigate whether LepMAP could predict IOH during anesthesia 1, 2 or 5 minutes before.
Detailed description
Hypothesis : the area under the ROC curves (ROC AUCs) at 1, 2 and 5 minutes of LepMAP would be superior to AMAP
Interventions
OTHERNo intervention
patients have benefited from maintenance wakefulness tests as part of their clinical evaluation
Sponsors
Hospices Civils de Lyon
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients suffering from sleep pathologies (apneas, narcolepsy, etc.) hospitalized for polysomnography and MWT, in order to evaluate their sleepiness (usually before they resume driving) * hospitalized in the Center for Sleep Medicine (Hôpital Lyon Croix Rousse) between September 2017 and January 2019
Exclusion criteria
* patient with active encephalopathy or epilepsy whose EEG was abnormal * denial of study participation * availability of all the recordings (n=4 tests) of the MWT
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| TThe primary endpoint was to determine if LepMAP was better than ΔMAP for the prediction of hypotensive event at 1, 2 and 5 minutes, defined as a mean arterial pressure of less than 65 mmHg | Only during perioperative period | the number of patients with MS during MWT as well as the mean number of MS per patient will be measured |
Countries
France
Contacts
Primary Contactlaure Peter-Derex
Outcome results
None listed