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Long-term Characterization of Patients With Severe/Critical Infection by COVID-19 Virus

Clinical, Radiological, Lung Function, and Quality of Life Characterization of Patients With Severe/Critical Infection by SARS-COV-2 (COVID-19) Virus, After 6 and 12 Months of Hospital Discharge

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04559100
Enrollment
112
Registered
2020-09-22
Start date
2020-11-15
Completion date
2022-07-01
Last updated
2024-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid19

Keywords

covid19, lung function, quality of life

Brief summary

A descriptive study to characterize clinical, radiological, lung function and quality of life alterations in patients who survived a severe or critical disease caused by SARS-COV-2 virus, who were treated in the intensive care unit of a high complexity institution in Cali, Colombia.

Interventions

RADIATIONchest radiography

6 and 12 months after hospital discharge. If the study is normal at 6 months it will not be repeated at 12 months.

RADIATIONthoracic computed tomography scan

6 and 12 months after hospital discharge, if the patient had a CT scan upon admission to the hospital. If the study is normal at 6 months it will not be repeated at 12 months.

DIAGNOSTIC_TESTspirometry

6 and 12 months after hospital discharge. If the study is normal at 6 months it will not be repeated at 12 months.

DIAGNOSTIC_TESTDiffusing capacity of carbon monoxide

6 and 12 months after hospital discharge. If the study is normal at 6 months it will not be repeated at 12 months.

DIAGNOSTIC_TEST6 minute walk test

6 and 12 months after hospital discharge. If the study is normal at 6 months it will not be repeated at 12 months.

DIAGNOSTIC_TESTsaint george respiratory questionnaire

6 and 12 months after hospital discharge.

Sponsors

Fundacion Clinica Valle del Lili
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No

Inclusion criteria

* ≥ 19 years old who had a positive test for SARS-COV-2 virus * Patients with a severe and critical disease by SARS-COV-2, who were treated at the ICU of Fundación Valle del Lili, and survived * Patients with chest radiography or CT scan at admission to the hospital

Exclusion criteria

* Patients who do not sign informed consent.

Design outcomes

Primary

MeasureTime frameDescription
Lung function6 months after hospital dischargeSpirometry in Liters
Radiological alterations6 months after hospital dischargeAlterations in chest radiography
Quality of life alterations6 months after hospital dischargeSaint George Respiratory questionnaire (from 0 to 100 points, higher levels indicating a major health impairment)

Countries

Colombia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026